Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10746258 | 0.98 | ESR1 (0.50) | ESR1ESR2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL19795462 | 0.98 | ESR1 (0.50) | ESR1ESR2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL13808874 | 0.95 | ESR1 (0.47) | ESR1ESR2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL14199384 | 0.93 | ESR1 (0.46) | ESR1ESR2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL4585187 | 0.92 | ESR1 (0.52) | ESR1ESR2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL11060353 | 0.91 | ESR1 (0.50) | ESR1ESR2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL25909565 | 0.87 | PTGS1 (0.65) | ESR1ESR2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL14570726 | 0.87 | PTGS1 (0.65) | ESR1ESR2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL13807875 | 0.84 | ESR1 (0.45) | ESR1ESR2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL1225178 | 0.83 | ESR1 (0.58) | ESR1ESR2PTGS2PTGS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957605-B1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-01-11 | — | — | EP | disclosed |
| EP-1957603-B1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-10-14 | — | — | EP | disclosed |
| US-8785001-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-8304095-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20080297037-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-12-04 | — | — | US | disclosed |
| US-20080272693-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-11-06 | — | — | US | disclosed |
| EP-1957605-A1 | ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2008-08-20 | — | — | EP | disclosed |
| EP-1957603-A1 | ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007065549-A1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |
| WO-2007065547-A1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080272693-A1 | Organic Electroluminescent Devices | EML4, MT-ND4L, EPCAM | ESR1 211/4885ESR2 417/4885PTGS2 3114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.