Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 11/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30606769 | 0.88 | FDPS (0.52) | FDPSLMNAGGPS1 | |
| SCHEMBL8061103 | 0.88 | FDPS (0.52) | FDPSLMNAGGPS1 | |
| SCHEMBL8343147 | 0.86 | FDPS (0.55) | FDPSLMNAGGPS1 | |
| SCHEMBL8343826 | 0.86 | FDPS (0.55) | FDPSLMNAGGPS1 | |
| SCHEMBL28906833 | 0.86 | FDPS (0.55) | FDPSLMNAGGPS1 | |
| SCHEMBL28791845 | 0.82 | FDPS (0.55) | FDPSSPHK1LMNAGGPS1 | |
| SCHEMBL28945250 | 0.82 | FDPS (0.55) | FDPSSPHK1LMNAGGPS1 | |
| SCHEMBL28791857 | 0.82 | FDPS (0.55) | FDPSSPHK1LMNAGGPS1 | |
| SCHEMBL7521059 | 0.81 | FDPS (0.46) | FDPSLMNAGGPS1 | |
| SCHEMBL28926746 | 0.79 | FDPS (0.52) | FDPSSPHK1LMNAGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603535-A4 | AROMATASE INHIBITOR DIAGNOSIS AND THERAPY | ETHICON INC (US) | 2008-10-15 | — | — | EP | disclosed |
| EP-1616182-A4 | ENZYME REPLACEMENT THERAPY WITH 17-BETA-HYDROXYSTEROID DEHYDROGENASE-TYPE 2 | ETHICON INC (US) | 2008-04-16 | — | — | EP | disclosed |
| EP-1616182-A2 | ENZYME REPLACEMENT THERAPY WITH 17-BETA-HYDROXYSTEROID DEHYDROGENASE-TYPE 2 | ETHICON, INC. (US) | 2006-01-18 | — | — | EP | disclosed |
| EP-1603535-A2 | AROMATASE INHIBITOR DIAGNOSIS AND THERAPY | ETHICON, INC. (US) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004082627-A2 | ENZYME REPLACEMENT THERAPY WITH 17-β-HYDROXYSTEROID DEHYDROGENASE-TYPE 2 | ETHICON, INC. (US) | 2004-09-30 | — | — | WO | disclosed |
| WO-2004082626-A2 | AROMATASE INHIBITOR DIAGNOSIS AND THERAPY | ETHICON, INC. (US) | 2004-09-30 | — | — | WO | disclosed |