SCHEMBL7521059

SCHEMBL7521059

CCCCCCCCCCCCCCCCC(CBr)C(O)(O)CCCCCCCCCCCCCCCC

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FDPS P14324 10/20 0.46
LMNA P02545 1/20 0.38
GGPS1 O95749 5/20 0.37
LCK P06239 1/20 0.37
PPARD Q03181 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
GPR84 Q9NQS5 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8061103 0.88 FDPS (0.52) FDPSLMNAGGPS1GPR84
SCHEMBL30606769 0.88 FDPS (0.52) FDPSLMNAGGPS1GPR84
SCHEMBL8343826 0.86 FDPS (0.55) FDPSLMNAGGPS1GPR84
SCHEMBL8343147 0.86 FDPS (0.55) FDPSLMNAGGPS1GPR84
SCHEMBL28906833 0.86 FDPS (0.55) FDPSLMNAGGPS1GPR84
SCHEMBL28791857 0.82 FDPS (0.55) FDPSLMNAGGPS1GPR84
SCHEMBL28791845 0.82 FDPS (0.55) FDPSLMNAGGPS1GPR84
SCHEMBL28945250 0.82 FDPS (0.55) FDPSLMNAGGPS1GPR84
SCHEMBL4585281 0.81 FDPS (0.46) FDPSLMNAGGPS1
SCHEMBL28926746 0.79 FDPS (0.52) FDPSLMNAGGPS1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6448047-B2 Sample processing to release nucleic acids for direct detection APPLIED GENE TECHNOLOGIES, INC. 2002-09-10 US disclosed
US-6423497-B1 LABELING PREFERENTIAL NUCLEOTIDE SEQUENCES; OBTAIN NUCLEIC ACIDS, INCUBATE IN AMPLIFICATION MIXTURE WITH LABEL AND BINDING AGENT, EXPOSE TO LIGHT, RECOVER PRODUCT APPLIED GENE TECHNOLOGIES, INC. 2002-07-23 US disclosed
US-20020061537-A1 Stabilization of nucleic acid amplification cocktails DATTAGUPTA NANIBHUSHAN (US) 2002-05-23 US disclosed
US-6379930-B1 Stabilization of nucleic acid amplification cocktails APPLIED GENE TECHNOLOGIES, INC. 2002-04-30 US disclosed
EP-1192272-A2 METHOD OF LABELING A NUCLEIC ACID AMPLICON WITH SIMULTANEOUS CONTAMINATION PREVENTION Applied Gene Technologies, Inc. (US) 2002-04-03 EP disclosed
WO-2002014548-A1 COMPOSITIONS AND METHODS FOR NUCLEIC ACIDS SAMPLE PROCESSING AND AMPLIFICATION APPLIED GENE TECHNOLOGIES, INC. (US) 2002-02-21 WO disclosed
US-20010031473-A1 Sample processing to release nucleic acids for direct detection DATTAGUPTA NANIBHUSHAN (US) 2001-10-18 US disclosed
US-6242188-B1 Sample processing to release nucleic acids for direct detection APPLIED GENE TECHNOLOGIES, INC. 2001-06-05 US disclosed
US-6187566-B1 COMPLEXES APPLIED GENE TECHNOLOGIES, INC. 2001-02-13 US disclosed
WO-2000053809-A2 METHOD OF LABELING A NUCLEIC ACID AMPLICON WITH SIMULTANEOUS CONTAMINATION PREVENTION APPLIED GENE TECHNOLOGIES, INC. (US) 2000-09-14 WO disclosed