Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.61 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427038 | 0.82 | NOTUM (0.44) | NOTUMATAD2DAOALDH1A1POLB | |
| SCHEMBL1082810 | 0.76 | NOTUM (1.00) | NOTUMATAD2KDM4EHPGDGAA | |
| SCHEMBL28513556 | 0.72 | ATAD2 (0.48) | NOTUMATAD2KDM4EHPGDGAA | |
| SCHEMBL30367674 | 0.72 | NOTUM (0.42) | NOTUMKDM4EHPGDDYRK1AGAA | |
| SCHEMBL31748649 | 0.71 | NOTUM (0.73) | NOTUMATAD2KDM4EHPGDGAA | |
| SCHEMBL11860616 | 0.71 | NOTUM (0.61) | NOTUMKDM4EHSD17B10LDHALDHB | |
| SCHEMBL27409174 | 0.69 | NOTUM (0.59) | NOTUMLDHALDHBCYP3A4ACHE | |
| SCHEMBL21237711 | 0.69 | ATAD2 (0.44) | NOTUMATAD2KDM4EHPGDGAA | |
| SCHEMBL2973655 | 0.68 | NOTUM (0.57) | NOTUMLDHALDHBCYP3A4ACHE | |
| SCHEMBL11119413 | 0.68 | NOTUM (0.57) | NOTUMKDM4EGAAHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708703-A4 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2008-04-09 | — | — | EP | disclosed |
| EP-1708703-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005059107-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2005-06-30 | — | — | WO | disclosed |