Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.34 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | LDHB | P07195 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22923873 | 0.80 | HTT (0.40) | KDM4EGAAHPGDHSD17B10ALDH1A1 | |
| SCHEMBL2124039 | 0.74 | DAO (0.37) | KDM4EDAOERCC1ERCC4GAA | |
| SCHEMBL2919647 | 0.74 | GPR35 (0.44) | NOTUMKDM4EGPR35GAAHPGD | |
| SCHEMBL16654880 | 0.74 | ALDH1A1 (0.33) | DAOERCC1ERCC4ALDH1A1GLA | |
| SCHEMBL16654461 | 0.74 | DAO (0.42) | KDM4EDAOERCC1ERCC4GAA | |
| SCHEMBL7422492 | 0.73 | DAO (0.35) | KDM4EDAOERCC1ERCC4HPGD | |
| SCHEMBL4585396 | 0.72 | NOTUM (0.61) | NOTUMKDM4EDYRK1ADAOGPR35 | |
| SCHEMBL19765249 | 0.72 | MEN1 (0.39) | NOTUMGPR35GAA | |
| SCHEMBL1725120 | 0.71 | DAO (0.34) | KDM4EDAOERCC1ERCC4GAA | |
| SCHEMBL16654409 | 0.69 | DAO (0.33) | DYRK1ADAOERCC1ERCC4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023155886-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |