Ethylene Glycol

Ethylene Glycol

SCHEMBL4585430

CC(COP(=O)(O)O)OP(=O)(O)O.OCCO.[NaH]

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.39
PGK2 P07205 1/20 0.39
PGD P52209 3/20 0.37
MPI P34949 1/20 0.37
ENPP2 Q13822 6/20 0.35
LPAR5 Q9H1C0 2/20 0.35
LPAR1 Q92633 2/20 0.35
LPAR3 Q9UBY5 2/20 0.35
LPAR6 P43657 1/20 0.35
LPAR4 Q99677 1/20 0.35
LPAR2 Q9HBW0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL10878300 0.96 PGK1 (0.39) PGK1PGK2PGDMPIENPP2
Ethylene Glycol SCHEMBL7862897 0.96 PGK1 (0.39) PGK1PGK2PGDMPIENPP2
SCHEMBL1574058 0.92 PGK1 (0.45) PGK1PGK2PGDMPIENPP2
SCHEMBL18132325 0.77 PGK1 (0.34) PGK1PGK2PGDMPIENPP2
SCHEMBL26188134 0.76 TSHR (0.35) LPAR5LPAR1LPAR3
SCHEMBL10952742 0.74 PGK1 (0.45) PGK1PGK2PGDMPIENPP2
SCHEMBL8407485 0.74 SMPD1 (0.36) PGK1PGK2ENPP2LPAR5LPAR1
SCHEMBL13636101 0.74 SMPD1 (0.36) PGK1PGK2ENPP2LPAR5LPAR1
SCHEMBL5432672 0.74 SMPD1 (0.36) PGK1PGK2
SCHEMBL2476321 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1575577-A4 COMPOSITION FOR THE PREVENTION AND TREATMENT OF INFLAMMATION OF THE EAR SINOFRESH HEALTHCARE INC (US) 2008-03-19 EP disclosed
EP-1575577-A2 COMPOSITION FOR THE PREVENTION AND TREATMENT OF INFLAMMATION OF THE EAR SinoFresh HealthCare, Inc. (US) 2005-09-21 EP disclosed
WO-2004047729-A2 COMPOSITION FOR THE PREVENTION AND TREATMENT OF INFLAMMATION OF THE EAR SINOFRESH HEALTHCARE, INC. (US) 2004-06-10 WO disclosed