SCHEMBL4585625

SCHEMBL4585625

O=C(NP(=O)(c1ccccc1)c1ccccc1)c1ccc(O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DEGS1 O15121 2/20 0.53
ESR1 P03372 2/20 0.50
CES2 O00748 1/20 0.48
KMT2A Q03164 5/20 0.47
MEN1 O00255 4/20 0.47
MPO P05164 1/20 0.47
CYP3A4 P08684 1/20 0.47
KDM5A P29375 1/20 0.47
BLM P54132 1/20 0.47
GFER P55789 1/20 0.47
PMP22 Q01453 1/20 0.47
HIF1A Q16665 1/20 0.47
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
GAA P10253 2/20 0.46
POLB P06746 3/20 0.46
KDM4E B2RXH2 1/20 0.46
MIF P14174 1/20 0.45
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31069857 0.88 HDAC3 (0.52) KMT2AMEN1RAB9ANPC1GAA
SCHEMBL4584936 0.81 KDM4E (0.56) KMT2AMEN1GFERRAB9ANPC1
SCHEMBL4585629 0.75 ESR1 (0.55) DEGS1ESR1KMT2AMEN1GAA
SCHEMBL672552 0.73 ESR1 (0.71) DEGS1ESR1CES2KMT2AMEN1
SCHEMBL4429088 0.73 ESR1 (0.71) DEGS1ESR1CES2KMT2AMEN1
SCHEMBL11688443 0.73 DEGS1 (0.83) DEGS1KMT2AMEN1RAB9ANPC1
SCHEMBL28627457 0.73 ESR1 (0.53) DEGS1ESR1CES2KMT2AMEN1
SCHEMBL28498103 0.72 HDAC3 (0.52) KMT2AMEN1RAB9ANPC1GAA
SCHEMBL22361764 0.72 NAPRT (0.45) ESR1KMT2AMEN1CYP3A4RAB9A
SCHEMBL14994124 0.71 ESR1 (0.68) DEGS1ESR1CES2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7396588-B2 Curable composition, varnish and laminate ZEON CORPORATION (JP) 2008-07-08 US disclosed
US-20070060674-A1 Curable composition, varnish and laminate ZEON CORPRATION (JP) 2007-03-15 US disclosed
US-7160609-B2 Curable composition, varnish, and layered product ZEON CORPORATION (JP) 2007-01-09 US disclosed
US-20040025743-A1 Curable composition, varnish, and layered product ZEON CORPORATION (JP) 2004-02-12 US disclosed