SCHEMBL4585629

SCHEMBL4585629

O=P(Nc1ccc(O)cc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.55
KCNA5 P22460 1/20 0.49
MAOA P21397 2/20 0.48
MAOB P27338 2/20 0.48
ESR2 Q92731 2/20 0.48
MMP2 P08253 3/20 0.47
DEGS1 O15121 2/20 0.47
MMP1 P03956 2/20 0.47
MMP9 P14780 2/20 0.47
LMNA P02545 3/20 0.44
KMT2A Q03164 2/20 0.44
GAA P10253 2/20 0.44
CA2 P00918 3/20 0.43
CA4 P22748 2/20 0.43
CA5A P35218 1/20 0.43
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
MAPT P10636 2/20 0.41
PTPN2 P17706 1/20 0.41
PTPN1 P18031 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16868500 0.87 KCNA5 (0.59) KCNA5LMNAKMT2ACA2CA4
SCHEMBL7533388 0.85 KCNA5 (0.58) ESR1KCNA5LMNAKMT2ACA2
Hydrochloric Acid SCHEMBL28020743 0.85 KCNA5 (0.58) KCNA5LMNAKMT2ACA2CA4
SCHEMBL4584942 0.81 KCNA5 (0.59) KCNA5MMP2MMP1MMP9LMNA
SCHEMBL4429088 0.78 ESR1 (0.71) ESR1MAOAMAOBESR2DEGS1
SCHEMBL672552 0.78 ESR1 (0.71) ESR1MAOAMAOBESR2DEGS1
SCHEMBL10051662 0.78 KCNA5 (0.47) KCNA5LMNAKMT2AMAPTMEN1
SCHEMBL14994124 0.76 ESR1 (0.68) ESR1MAOAMAOBESR2DEGS1
SCHEMBL4585625 0.75 DEGS1 (0.53) ESR1MAOAMAOBESR2DEGS1
SCHEMBL15683062 0.74 ESR1 (0.65) ESR1ESR2DEGS1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7396588-B2 Curable composition, varnish and laminate ZEON CORPORATION (JP) 2008-07-08 US disclosed
US-20070060674-A1 Curable composition, varnish and laminate ZEON CORPRATION (JP) 2007-03-15 US disclosed
US-7160609-B2 Curable composition, varnish, and layered product ZEON CORPORATION (JP) 2007-01-09 US disclosed
US-20040025743-A1 Curable composition, varnish, and layered product ZEON CORPORATION (JP) 2004-02-12 US disclosed