Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | CSF1R | P07333 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4585709 | 1.00 | ENPP2 (0.39) | ENPP2CSF1RMEN1KMT2AMAPK10 | |
| Trifluoroacetic Acid SCHEMBL4585816 | 0.93 | MEN1 (0.37) | ENPP2MEN1KMT2AKDM4ETP53 | |
| Trifluoroacetic Acid SCHEMBL4585836 | 0.93 | MEN1 (0.37) | ENPP2MEN1KMT2AKDM4ETP53 | |
| Trifluoroacetic Acid SCHEMBL2988374 | 0.92 | MEN1 (0.47) | ENPP2MEN1KMT2AMAPK10MAPT | |
| Trifluoroacetic Acid SCHEMBL5048553 | 0.92 | MEN1 (0.47) | ENPP2MEN1KMT2AMAPK10MAPT | |
| SCHEMBL4585717 | 0.91 | MEN1 (0.38) | ENPP2CSF1RMEN1KMT2AMAPK10 | |
| Trifluoroacetic Acid SCHEMBL2990510 | 0.89 | ENPP2 (0.40) | ENPP2CSF1RMEN1KMT2AKDM4E | |
| Trifluoroacetic Acid SCHEMBL2990505 | 0.89 | ENPP2 (0.40) | ENPP2CSF1RMEN1KMT2AKDM4E | |
| Trifluoroacetic Acid SCHEMBL2988379 | 0.88 | ENPP2 (0.37) | ENPP2MEN1KMT2AKDM4ETP53 | |
| Trifluoroacetic Acid SCHEMBL5048576 | 0.86 | MAPT (0.43) | MEN1KMT2AMAPK10TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879563-A4 | NOVEL CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2008-07-16 | — | — | EP | disclosed |
| EP-1879563-A2 | NOVEL CHEMICAL COMPOUNDS | Smithkline Beecham Corporation (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006132739-A2 | NOVEL CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-12-14 | — | — | WO | disclosed |