Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 3/20 | 0.62 |
| ▸ | PRCP | P42785 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11575529 | 0.80 | TAAR1 (0.52) | GAADRD2DRD1CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL28131938 | 0.78 | SLC22A1 (0.53) | PRCPKDM1ATSHRNPSR1 | |
| Urea SCHEMBL28007088 | 0.76 | PRCP (0.81) | GID4PRCPGAAKDM1ADRD2 | |
| Carbamic Acid SCHEMBL9226170 | 0.76 | PRCP (0.81) | GID4PRCPGAAKDM1ADRD2 | |
| Urea SCHEMBL27886692 | 0.75 | GAA (0.81) | GID4PRCPGAAKDM1ADRD2 | |
| SCHEMBL28007086 | 0.74 | PRCP (0.76) | GID4PRCPGAAKDM1ADRD2 | |
| SCHEMBL18938979 | 0.72 | GID4 (0.41) | GID4DRD2DRD1TSHRNPSR1 | |
| SCHEMBL5969300 | 0.72 | PRCP (0.54) | GID4PRCPGAARECQLTSHR | |
| Oxalic Acid SCHEMBL1695318 | 0.71 | PRCP (0.83) | GID4PRCPGAAKDM1ADRD2 | |
| Oxalic Acid SCHEMBL1695320 | 0.71 | PRCP (0.83) | GID4PRCPGAAKDM1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408744-A1 | BICYCLIC COMPOUNDS AS INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | Schering Corporation (US) | 2012-01-25 | — | — | EP | disclosed |