Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14855323 | 1.00 | KCNH2 (0.49) | KCNH2CNR2SIGMAR1ALDH1A1PKM | |
| SCHEMBL4585544 | 1.00 | KCNH2 (0.49) | KCNH2CNR2SIGMAR1ALDH1A1PKM | |
| SCHEMBL7272835 | 0.93 | ALDH1A1 (0.46) | KCNH2ALDH1A1PKMBCHE | |
| SCHEMBL10590827 | 0.87 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1BCHEACHE | |
| SCHEMBL10589011 | 0.87 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1BCHEACHE | |
| SCHEMBL8857301 | 0.86 | ALDH1A1 (0.48) | SIGMAR1ALDH1A1DRD2OPRM1DRD3 | |
| SCHEMBL5542599 | 0.85 | SIGMAR1 (0.57) | KCNH2SIGMAR1ALDH1A1 | |
| SCHEMBL5542089 | 0.85 | SIGMAR1 (0.57) | KCNH2SIGMAR1ALDH1A1 | |
| SCHEMBL11824111 | 0.83 | KCNH2 (0.49) | KCNH2CNR2SIGMAR1ALDH1A1DRD2 | |
| SCHEMBL5537797 | 0.83 | SIGMAR1 (0.54) | KCNH2SIGMAR1ALDH1A1OPRM1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008113992-A2 | GEL COMPOSITIONS COMPRISING UREA DERIVATIVES | PLIVA HRVATSKA D.O.O. (HR) | 2008-09-25 | — | — | WO | disclosed |