⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9292 | 0.72 | — | — | |
| SCHEMBL634286 | 0.69 | — | — | |
| SCHEMBL2542572 | 0.67 | — | — | |
| SCHEMBL227419 | 0.67 | — | — | |
| SCHEMBL3760197 | 0.67 | — | — | |
| SCHEMBL98755 | 0.67 | — | — | |
| SCHEMBL1426682 | 0.67 | — | — | |
| SCHEMBL514568 | 0.67 | — | — | |
| SCHEMBL249451 | 0.67 | — | — | |
| SCHEMBL271044 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534823-A4 | THE USE OF ISOCYANATE LINKERS TO MAKE HYDROLYZABLE ACTIVE AGENT BIOPOLYMER CONJUGATES | BIOMARIN PHARM INC (US) | 2008-12-31 | — | — | EP | disclosed |
| US-20060029586-A1 | Use of isocyanate linkers to make hydrolyzable active agent biopolymer conjugates | BIOMARIN PHARMACEUTICAL INC. | 2006-02-09 | — | — | US | disclosed |
| WO-2005007663-A9 | FLUOROGENIC ENZYME SUBSTRATES AND USES THEREOF | IRM LLC (US) | 2005-09-15 | — | — | WO | disclosed |
| US-20050153306-A1 | Fluorogenic enzyme substrates and uses thereof | IRM LLC (BM) | 2005-07-14 | — | — | US | disclosed |
| EP-1534823-A2 | THE USE OF ISOCYANATE LINKERS TO MAKE HYDROLYZABLE ACTIVE AGENT BIOPOLYMER CONJUGATES | BioMarin Pharmaceutical Inc. (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2005007663-A2 | FLUOROGENIC ENZYME SUBSTRATES AND USES THEREOF | IRM LLC (BM) | 2005-01-27 | — | — | WO | disclosed |
| US-20040176270-A1 | Use of isocyanate linkers to make hydrolyzable active agent biopolymer conjugates | BIOMARIN PHARMACEUTICAL INC. | 2004-09-09 | — | — | US | disclosed |
| WO-2004008101-A2 | THE USE OF ISOCYANATE LINKERS TO MAKE HYDROLYZABLE ACTIVE AGENT BIOPOLYMER CONJUGATES | BIOMARIN PHARMACEUTICAL INC. (US) | 2004-01-22 | — | — | WO | disclosed |
| EP-0776330-B1 | PHOTOLABILE COMPOUNDS AND METHODS FOR THEIR USE | AFFYMAX TECH NV (AN) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002099078-A2 | FUNCTIONAL PROTEOMIC PROFILING | IRM LLC (BM) | 2002-12-12 | — | — | WO | disclosed |
| US-5917016-A | USEFUL AS PHOTOCLEAVABLE LINKING GROUPS IN SOLID PHASE SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (GB) | 1999-06-29 | — | — | US | disclosed |
| US-5874589-A | Methods for synthesizing diverse collections of tetramic acids and derivatives thereof | GLAXO WELLCOME, INC. (US) | 1999-02-23 | — | — | US | disclosed |
| US-5846839-A | Methods for hard-tagging an encoded synthetic library | GLAXO GROUP LIMITED (GB) | 1998-12-08 | — | — | US | disclosed |
| US-5739386-A | PHOTOCLEAVABLE LINKING GROUPS IN SOLID PHASE SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (GB) | 1998-04-14 | — | — | US | disclosed |
| WO-1997041093-A1 | METHODS FOR THE SYNTHESIS OF FMOC PROTECTED AMINES | AFFYMAX TECHNOLOGIES N.V. (GB) | 1997-11-06 | — | — | WO | disclosed |
| EP-0776330-A2 | PHOTOLABILE COMPOUNDS AND METHODS FOR THEIR USE | AFFYMAX TECHNOLOGIES N.V. (AN) | 1997-06-04 | — | — | EP | disclosed |
| US-5549974-A | IMMOBILIZATION | AFFYMAX TECHNOLOGIES NV (AN) | 1996-08-27 | — | — | US | disclosed |
| WO-1996000148-A1 | METHODS FOR THE SOLID PHASE SYNTHESIS OF THIAZOLIDINONES, METATHIAZANONES, AND DERIVATIVES THEREOF | AFFYMAX TECHNOLOGIES N.V. (AN) | 1996-01-04 | — | — | WO | disclosed |
| WO-1996000378-A1 | PHOTOLABILE COMPOUNDS AND METHODS FOR THEIR USE | AFFYMAX TECHNOLOGIES N.V. (AN) | 1996-01-04 | — | — | WO | disclosed |
| WO-1995018971-A1 | METHODS FOR THE SOLID PHASE SYNTHESIS OF GLYCOCONJUGATES | AFFYMAX TECHNOLOGIES N.V. (NL) | 1995-07-13 | — | — | WO | disclosed |