Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | CSF1R | P07333 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | MELK | Q14680 | 8/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585167 | 0.93 | CSF1R (0.51) | ENPP2CSF1RMEN1KMT2AMAPK10 | |
| SCHEMBL4585846 | 0.91 | MEN1 (0.47) | ENPP2MEN1KMT2AMELKALDH1A1 | |
| SCHEMBL4585835 | 0.91 | MEN1 (0.47) | ENPP2MEN1KMT2AMELKALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL2999021 | 0.90 | CSF1R (0.47) | ENPP2CSF1RMEN1KMT2AMAPK10 | |
| Trifluoroacetic Acid SCHEMBL2999023 | 0.90 | CSF1R (0.47) | ENPP2CSF1RMEN1KMT2AMAPK10 | |
| SCHEMBL5054187 | 0.90 | MEN1 (0.58) | ENPP2CSF1RMEN1KMT2AMAPK10 | |
| SCHEMBL2993867 | 0.90 | MEN1 (0.58) | ENPP2CSF1RMEN1KMT2AMAPK10 | |
| SCHEMBL2993870 | 0.85 | ENPP2 (0.43) | ENPP2CSF1RMEN1KMT2AMAPK10 | |
| SCHEMBL4585691 | 0.84 | CISD1 (0.41) | ENPP2CSF1RMEN1KMT2ACISD1 | |
| SCHEMBL4585695 | 0.84 | CISD1 (0.41) | ENPP2CSF1RMEN1KMT2ACISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879563-A4 | NOVEL CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2008-07-16 | — | — | EP | disclosed |
| EP-1879563-A2 | NOVEL CHEMICAL COMPOUNDS | Smithkline Beecham Corporation (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006132739-A2 | NOVEL CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-12-14 | — | — | WO | disclosed |