Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16561709 | 1.00 | ALDH1A1 (0.45) | ALDH1A1ATMTSHRLMNACYP1A2 | |
| SCHEMBL18078270 | 0.96 | NAAA (0.43) | ALDH1A1ATMTSHRLMNACYP1A2 | |
| SCHEMBL26789944 | 0.87 | CA1 (0.42) | ALDH1A1ATMTSHRLMNACYP1A2 | |
| SCHEMBL10308586 | 0.83 | SLC7A5 (0.41) | ALDH1A1ATMMAPK1HCAR2 | |
| SCHEMBL15936938 | 0.83 | SLC7A5 (0.41) | ALDH1A1ATMMAPK1HCAR2 | |
| SCHEMBL1923182 | 0.82 | ALDH1A1 (0.50) | ALDH1A1ATMTSHRLMNACYP1A2 | |
| SCHEMBL7786498 | 0.82 | ALDH1A1 (0.50) | ALDH1A1ATMTSHRLMNACYP1A2 | |
| SCHEMBL14242995 | 0.82 | ALDH1A1 (0.50) | ALDH1A1ATMTSHRLMNACYP1A2 | |
| SCHEMBL1923181 | 0.82 | ALDH1A1 (0.50) | ALDH1A1ATMTSHRLMNACYP1A2 | |
| SCHEMBL17030299 | 0.81 | ALDH1A1 (0.36) | ALDH1A1ATMTSHRLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758540-A4 | PURIFICATION OF INSULIN-LIKE MATERIAL BY REVERSE PHASE CHROMATOGRAPHY | WOCKHARDT LTD (IN) | 2007-06-20 | — | — | EP | claimed |
| EP-1758540-A1 | PURIFICATION OF INSULIN-LIKE MATERIAL BY REVERSE PHASE CHROMATOGRAPHY | Wockhardt Limited (IN) | 2007-03-07 | — | — | EP | claimed |
| WO-2005115303-A1 | PURIFICATION OF INSULIN-LIKE MATERIAL BY REVERSE PHASE CHROMATOGRAPHY | WOCKHARDT LIMITED (IN) | 2005-12-08 | — | — | WO | claimed |
| US-20170196879-A1 | Use of Inhibitor of Apoptosis Protein (IAP) Antagonists in HIV Therapy | Sanford Burnham Prebys Medical Discovery Institute | 2017-07-13 | — | — | US | disclosed |
| US-20170081362-A1 | Inhibitor of Apoptosis Protein (IAP) Antagonists | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | 2017-03-23 | — | — | US | disclosed |
| US-9546174-B2 | Inhibitor of apoptosis protein (IAP) antagonists | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2017-01-17 | — | — | US | disclosed |
| WO-2015187998-A2 | USE OF INHIBITOR OF APOPTOSIS PROTEIN (IAP) ANTAGONISTS IN HIV THERAPY | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2015-12-10 | — | — | WO | disclosed |
| US-20150307499-A1 | INHIBITOR OF APOPTOSIS PROTEIN (IAP) ANTAGONISTS | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | 2015-10-29 | — | — | US | disclosed |
| WO-2014085489-A1 | INHIBITOR OF APOPTOSIS PROTEIN (IAP) ANTAGONISTS | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2014-06-05 | — | — | WO | disclosed |
| EP-1581627-A4 | YEAST PROTEIN EXPRESSION SECRETION SYSTEM | WOCKHARDT LTD (IN) | 2008-06-11 | — | — | EP | disclosed |
| US-20080108787-A1 | Purification of Insulin-Like Material by Reverse Phase Chromatography | WOCKHARDT LIMITED (IN) | 2008-05-08 | — | — | US | disclosed |
| EP-1758540-A4 | PURIFICATION OF INSULIN-LIKE MATERIAL BY REVERSE PHASE CHROMATOGRAPHY | WOCKHARDT LTD (IN) | 2007-06-20 | — | — | EP | disclosed |
| EP-1758540-A1 | PURIFICATION OF INSULIN-LIKE MATERIAL BY REVERSE PHASE CHROMATOGRAPHY | Wockhardt Limited (IN) | 2007-03-07 | — | — | EP | disclosed |
| US-20060234351-A1 | Yeast protein expression secretion system | WOCHARDT LIMITED (IN) | 2006-10-19 | — | — | US | disclosed |
| WO-2005115303-A1 | PURIFICATION OF INSULIN-LIKE MATERIAL BY REVERSE PHASE CHROMATOGRAPHY | WOCKHARDT LIMITED (IN) | 2005-12-08 | — | — | WO | disclosed |
| EP-1581627-A2 | YEAST PROTEIN EXPRESSION SECRETION SYSTEM | Wockhardt Limited (IN) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004024862-A2 | YEAST PROTEIN EXPRESSION SECRETION SYSTEM | WOCKHARDT LIMITED (IN) | 2004-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170081362-A1 | Inhibitor of Apoptosis Protein (IAP) Antagonists | API5, XIAP, BIRC5 | ALDH1A1 4555/4885ATM 1822/4885TSHR 4582/4885 |
| US-20170196879-A1 | Use of Inhibitor of Apoptosis Protein (IAP) Antagonists in HIV Therapy | API5, BIRC3, XIAP | ALDH1A1 2629/4885ATM 2911/4885TSHR 4807/4885 |
| US-20150307499-A1 | INHIBITOR OF APOPTOSIS PROTEIN (IAP) ANTAGONISTS | API5, XIAP, BIRC5 | ALDH1A1 4556/4885ATM 1783/4885TSHR 4620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.