Sugi Predict

Sugi Predict / Compounds / SCHEMBL1770021

SCHEMBL1770021

SCHEMBL1770021

Cc1nc2ccc(N)cc2nc1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.53
▸ TLR9 Q9NR96 2/20 0.53
▸ ATM Q13315 1/20 0.53
▸ KDM4E B2RXH2 5/20 0.52
▸ LMNA P02545 2/20 0.52
▸ POLB P06746 1/20 0.52
▸ CASP6 P55212 1/20 0.52
▸ DYRK1A Q13627 2/20 0.51
▸ CDC7 O00311 1/20 0.51
▸ EEF2K O00418 1/20 0.51
▸ PLK4 O00444 1/20 0.51
▸ AURKA O14965 1/20 0.51
▸ DYRK3 O43781 1/20 0.51
▸ RPS6KA5 O75582 1/20 0.51
▸ PRKD3 O94806 1/20 0.51
▸ MAP4K4 O95819 1/20 0.51
▸ PIM1 P11309 1/20 0.51
▸ PHKG2 P15735 1/20 0.51
▸ CDK2 P24941 1/20 0.51
▸ AKT1 P31749 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30343134 1.00 KMT2A (0.53) KMT2ATLR9ATMKDM4ELMNA
SCHEMBL4586206 0.85 KMT2A (0.67) KMT2ATLR9ATMKDM4ELMNA
SCHEMBL29922808 0.85 KMT2A (0.67) KMT2ATLR9ATMKDM4ELMNA
SCHEMBL3480837 0.85 KMT2A (0.67) KMT2ATLR9ATMKDM4ELMNA
SCHEMBL22288213 0.82 KMT2A (0.61) KMT2ATLR9ATMKDM4ELMNA
SCHEMBL22288240 0.82 KMT2A (0.61) KMT2ATLR9ATMKDM4ELMNA
SCHEMBL31087686 0.82 KMT2A (0.61) KMT2ATLR9ATMKDM4ELMNA
SCHEMBL1782038 0.82 KMT2A (0.43) KMT2ATLR9ATMKDM4ELMNA
Hydrochloric Acid SCHEMBL7566148 0.82 KMT2A (0.64) KMT2ATLR9ATMKDM4ELMNA
SCHEMBL12964185 0.80 KMT2A (0.57) KMT2ATLR9ATMKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100256132-A1 IL-12 MODULATORY COMPOUNDS SYNTA PHARMACEUTICALS CORPORATION (US) 2010-10-07 — — US claimed
EP-1819341-A2 IL-12 MODULATORY COMPOUNDS Synta Pharmaceuticals Corporation (US) 2007-08-22 — — EP claimed
US-20060223996-A1 IL-12 modulatory compounds SYNTA PHARMACEUTICALS CORP. (US) 2006-10-05 — — US claimed
WO-2006053227-A2 IL-12 MODULATORY COMPOUNDS SYNTA PHARMACEUTICALS CORP. (US) 2006-05-18 — — WO claimed
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 — — EP claimed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 — — US claimed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 — — EP claimed
US-20250282748-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2025-09-11 — — US disclosed
CN-113292539-B Substituted oxopyridine derivatives 拜耳制药股份公司 2023-12-22 — — CN disclosed
CN-113929618-B Oxo-pyridine amide derivative, preparation method and medical application thereof 江苏恒瑞医药股份有限公司 2023-08-11 — — CN disclosed
CN-113912586-B Oxopyridine amide derivatives, preparation method thereof and application thereof in medicines 江苏恒瑞医药股份有限公司 2023-04-07 — — CN disclosed
US-20230024752-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2023-01-26 — — US disclosed
CN-113929618-A Oxopyridine amide derivatives, preparation method thereof and application thereof in medicines 江苏恒瑞医药股份有限公司 2022-01-14 — — CN disclosed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 — — US disclosed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 — — EP disclosed
US-4118232-A Photographic material containing sulphonic acid group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1978-10-03 — — US disclosed
US-4051123-A Sulfonic-acid-group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1977-09-27 — — US disclosed
US-4014698-A ACIDS, IODIDE COMPOUNDS, OXIDIZERS, DIAZINE COMPOUND CIBA-GEIGY AG (CH) 1977-03-29 — — US disclosed
US-3957860-A SULFAMIC ACID CIBA-GEIGY AG (CH) 1976-05-18 — — US disclosed
US-3931142-A Heterocyclic containing disazo compounds CIBA-GEIGY AG (CH) 1976-01-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060223996-A1 IL-12 modulatory compounds IL2, IL4, IFNG KMT2A 3672/4885TLR9 264/4885ATM 4046/4885
US-20250282748-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES OGFOD1, VASP, PNPO KMT2A 4384/4885TLR9 2565/4885ATM 1505/4885
US-20230024752-A1 SUBSTITUTED OXOPYRIDINE DERIVATIVES OGFOD1, VASP, PNPO KMT2A 4384/4885TLR9 2565/4885ATM 1505/4885
US-20100256132-A1 IL-12 MODULATORY COMPOUNDS IL2, IL4, IFNG KMT2A 3672/4885TLR9 264/4885ATM 4046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.