Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14716260 | 0.89 | TSHR (0.56) | TSHRNPSR1RAB9ANPC1KMT2A | |
| SCHEMBL16592204 | 0.89 | RAB9A (0.51) | TSHRNPSR1RAB9ANPC1KMT2A | |
| SCHEMBL15410033 | 0.86 | NPC1 (0.54) | TSHRNPSR1RAB9ANPC1KMT2A | |
| SCHEMBL16589426 | 0.86 | NPSR1 (0.51) | TSHRNPSR1RAB9ANPC1KMT2A | |
| SCHEMBL7363838 | 0.82 | KMT2A (0.59) | RAB9ANPC1KMT2AMEN1KCNK3 | |
| SCHEMBL2915005 | 0.80 | TSHR (0.56) | TSHRNPSR1RAB9AKMT2AMEN1 | |
| SCHEMBL11634323 | 0.80 | NPC1 (0.50) | RAB9ANPC1KMT2AMEN1KCNK3 | |
| SCHEMBL17803643 | 0.79 | RAB9A (0.58) | RAB9ANPC1KMT2AMEN1KCNK3 | |
| SCHEMBL22120885 | 0.77 | HDAC1 (0.56) | RAB9ANPC1KMT2AMEN1LMNA | |
| SCHEMBL4039962 | 0.75 | KMT2A (0.58) | RAB9ANPC1KMT2AMEN1KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814890-A4 | ISOTACTIC POLYPROPYLENE CONTAINING POLYMERS | CORNELL RES FOUNDATION INC (US) | 2008-10-08 | — | — | EP | disclosed |
| US-7300994-B2 | Isotactic polypropylene containing polymers | CORNELL RESEARCH FOUNDATION, INC. (US) | 2007-11-27 | — | — | US | disclosed |
| EP-1814890-A2 | ISOTACTIC POLYPROPYLENE CONTAINING POLYMERS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006057850-A2 | ISOTACTIC POLYPROPYLENE CONTAINING POLYMERS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2006-06-01 | — | — | WO | disclosed |
| US-20060111528-A1 | Isotactic polypropylene containing polymers | CORNELL RESEARCH FOUNDATION INC. (US) | 2006-05-25 | — | — | US | disclosed |