Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MDM4 | O15151 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586310 | 0.86 | TSHR (0.60) | NPC1RAB9ATSHRNPSR1KCNK3 | |
| SCHEMBL15410493 | 0.84 | TSHR (0.42) | NPC1RAB9ATSHRNPSR1LMNA | |
| SCHEMBL15409614 | 0.84 | RAB9A (0.52) | NPC1RAB9AKCNJ11LMNAKMT2A | |
| SCHEMBL15410034 | 0.84 | KCNJ11 (0.47) | NPC1RAB9ANPSR1KCNJ11LMNA | |
| SCHEMBL15410726 | 0.83 | TRPV1 (0.59) | NPC1RAB9ANPSR1KMT2AMEN1 | |
| SCHEMBL15411914 | 0.82 | NPSR1 (0.55) | NPC1RAB9AP2RX1TSHRNPSR1 | |
| SCHEMBL15411037 | 0.82 | ABCC9 (0.52) | RAB9ATSHRNPSR1KCNJ11KCNK3 | |
| SCHEMBL15410723 | 0.82 | KCNJ11 (0.52) | NPC1RAB9AP2RX1TSHRNPSR1 | |
| SCHEMBL15411277 | 0.82 | KCNK3 (0.56) | NPC1RAB9ATSHRNPSR1KCNJ11 | |
| SCHEMBL15412057 | 0.82 | NPC1 (0.61) | NPC1RAB9ALMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140018566-A1 | PALLADIUM(II)-CATALYZED SELECTIVE FLUORINATION OF BENZOIC ACIDS AND DERIVATIVES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018566-A1 | PALLADIUM(II)-CATALYZED SELECTIVE FLUORINATION OF BENZOIC ACIDS AND DERIVATIVES | AHR, DDT, AOC2 | NPC1 2304/4885RAB9A 661/4885P2RX1 2449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.