Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | HTR6 | P50406 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 3/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989207 | 0.88 | CA1 (0.64) | MMP2CA1CA2MMP1MMP9 | |
| SCHEMBL11348903 | 0.88 | CA1 (0.64) | MMP2CA1CA2MMP1MMP9 | |
| SCHEMBL30444901 | 0.88 | CA1 (0.64) | MMP2CA1CA2MMP1MMP9 | |
| SCHEMBL9132217 | 0.86 | CA1 (0.62) | MMP2CA1CA2MMP1MMP9 | |
| SCHEMBL9133243 | 0.86 | CA1 (0.62) | MMP2CA1CA2MMP1MMP9 | |
| SCHEMBL9133026 | 0.86 | CA1 (0.62) | MMP2CA1CA2MMP1MMP9 | |
| SCHEMBL9135099 | 0.86 | CA1 (0.62) | MMP2CA1CA2MMP1MMP9 | |
| SCHEMBL9132788 | 0.86 | CA1 (0.62) | MMP2CA1CA2MMP1MMP9 | |
| SCHEMBL9134117 | 0.86 | CA1 (0.62) | MMP2CA1CA2MMP1MMP9 | |
| SCHEMBL9134578 | 0.86 | CA1 (0.62) | MMP2CA1CA2MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565448-A4 | METHOD OF PREPARING 10H-DIBENZO b,f 1,4 THIAZEPIN-11-ONE | SK HOLDINGS CO LTD (KR) | 2008-04-23 | — | — | EP | claimed |
| US-7214793-B2 | Method of preparing 10H-dibenzo[b,f][11,4]thiazepin-11-one | SK CORPORATION (KR) | 2007-05-08 | — | — | US | claimed |
| US-20070066589-A1 | Reacting dithiodisalicylic acid with 1-chloro-2-nitrobenzene in a basic aqueous solution; reducing the nitro group of the 2-(2-nitrophenylthio)benzoic acid formed with hydrogen gas, a solvent and a heterogeneous metal catalyst; and cyclizing the product in an organic solvent | SK BIOTEK CO., LTD. (KR) | 2007-03-22 | — | — | US | claimed |
| EP-1565448-A2 | METHOD OF PREPARING 10H-DIBENZO b,f 1,4 THIAZEPIN-11-ONE | SK Corporation (KR) | 2005-08-24 | — | — | EP | claimed |
| WO-2004047722-A2 | METHOD OF PREPARING 10H-DIBENZO[b,f][1,4]THIAZEPIN-11-ONE | SK CORPORATION (KR) | 2004-06-10 | — | — | WO | claimed |
| EP-1565448-A4 | METHOD OF PREPARING 10H-DIBENZO b,f 1,4 THIAZEPIN-11-ONE | SK HOLDINGS CO LTD (KR) | 2008-04-23 | — | — | EP | disclosed |
| EP-1565448-A4 | METHOD OF PREPARING 10H-DIBENZO b,f 1,4 THIAZEPIN-11-ONE | SK HOLDINGS CO LTD (KR) | 2008-04-23 | — | — | EP | disclosed |
| US-7214793-B2 | Method of preparing 10H-dibenzo[b,f][11,4]thiazepin-11-one | SK CORPORATION (KR) | 2007-05-08 | — | — | US | disclosed |
| US-7214793-B2 | Method of preparing 10H-dibenzo[b,f][11,4]thiazepin-11-one | SK CORPORATION (KR) | 2007-05-08 | — | — | US | disclosed |
| US-20070066589-A1 | Reacting dithiodisalicylic acid with 1-chloro-2-nitrobenzene in a basic aqueous solution; reducing the nitro group of the 2-(2-nitrophenylthio)benzoic acid formed with hydrogen gas, a solvent and a heterogeneous metal catalyst; and cyclizing the product in an organic solvent | SK BIOTEK CO., LTD. (KR) | 2007-03-22 | — | — | US | disclosed |
| US-20070066589-A1 | Reacting dithiodisalicylic acid with 1-chloro-2-nitrobenzene in a basic aqueous solution; reducing the nitro group of the 2-(2-nitrophenylthio)benzoic acid formed with hydrogen gas, a solvent and a heterogeneous metal catalyst; and cyclizing the product in an organic solvent | SK BIOTEK CO., LTD. (KR) | 2007-03-22 | — | — | US | disclosed |
| EP-1565448-A2 | METHOD OF PREPARING 10H-DIBENZO b,f 1,4 THIAZEPIN-11-ONE | SK Corporation (KR) | 2005-08-24 | — | — | EP | disclosed |
| EP-1565448-A2 | METHOD OF PREPARING 10H-DIBENZO b,f 1,4 THIAZEPIN-11-ONE | SK Corporation (KR) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004047722-A8 | METHOD OF PREPARING 10H-DIBENZO[b,f][1,4]THIAZEPIN-11-ONE | SK CORP (KR) | 2005-07-21 | — | — | WO | disclosed |
| WO-2004047722-A3 | METHOD OF PREPARING 10H-DIBENZO[b,f][1,4]THIAZEPIN-11-ONE | SK CORP (KR) | 2004-12-02 | — | — | WO | disclosed |
| WO-2004047722-A2 | METHOD OF PREPARING 10H-DIBENZO[b,f][1,4]THIAZEPIN-11-ONE | SK CORPORATION (KR) | 2004-06-10 | — | — | WO | disclosed |
| WO-2004047722-A2 | METHOD OF PREPARING 10H-DIBENZO[b,f][1,4]THIAZEPIN-11-ONE | SK CORPORATION (KR) | 2004-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066589-A1 | Reacting dithiodisalicylic acid with 1-chloro-2-nitrobenzene in a basic aqueous solution; reducing the nitro group of the 2-(2-nitrophenylthio)benzoic acid formed with hydrogen gas, a solvent and a heterogeneous metal catalyst; and cyclizing the product in an organic solvent | PTGS1, PTGS2, CA2 | GAA 3512/4885HTR6 1296/4885MMP2 3053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.