Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 6/20 | 0.32 |
| ▸ | NPY1R | P25929 | 5/20 | 0.32 |
| ▸ | NPY2R | P49146 | 4/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.32 |
| ▸ | FNTA | P49354 | 9/20 | 0.32 |
| ▸ | FNTB | P49356 | 9/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 9/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.30 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.30 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.30 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.30 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.30 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.30 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL23242474 | 0.93 | OTC (0.34) | NPY4RNPY1RNPY2RNPY5RFNTA | |
| Arginine SCHEMBL23242198 | 0.93 | OTC (0.34) | NPY4RNPY1RNPY2RNPY5RFNTA | |
| Arginine SCHEMBL15676652 | 0.93 | OTC (0.34) | NPY4RNPY1RNPY2RNPY5RFNTA | |
| Arginine SCHEMBL23242195 | 0.93 | OTC (0.34) | NPY4RNPY1RNPY2RNPY5RFNTA | |
| Arginine SCHEMBL5060815 | 0.92 | OTC (0.35) | NPY4RNPY1RNPY2RNPY5RTUBB4A | |
| Arginine SCHEMBL21612207 | 0.92 | OTC (0.35) | NPY4RNPY1RNPY2RNPY5RTUBB4A | |
| Arginine SCHEMBL8319070 | 0.92 | OTC (0.35) | NPY4RNPY1RNPY2RNPY5RTUBB4A | |
| Arginine SCHEMBL18920531 | 0.92 | OTC (0.35) | NPY4RNPY1RNPY2RNPY5RTUBB4A | |
| Arginine SCHEMBL6435765 | 0.90 | GLP1R (0.32) | — | |
| Arginine SCHEMBL2337389 | 0.89 | GSR (0.39) | NPY4RNPY1RNPY2RNPY5RTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7464088-B1 | Architecture for efficient pattern match operations | SAGE-N RESEARCH, INC. (US) | 2008-12-09 | — | — | US | disclosed |