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Arginine

Arginine

SCHEMBL6435765

C[C@H](N)C(=O)O.N=C(N)NCCC[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NCC(=O)O.N[C@@H](CC(=O)O)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACE

The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 4/20 0.32
▸ SCTR P47872 1/20 0.32
▸ KLK7 P49862 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arginine SCHEMBL27640159 0.95 GLP1R (0.33) GLP1RKLK7
Cystine SCHEMBL10538206 0.94 GLP1R (0.33) GLP1RSCTR
Arginine SCHEMBL27629650 0.92 GLP1R (0.34) GLP1RSCTR
Cystine SCHEMBL27709554 0.91 GLP1R (0.32) GLP1RKLK7
Arginine SCHEMBL6481630 0.90 GLP1R (0.35) GLP1R
Arginine SCHEMBL4587139 0.90 NPY4R (0.32) —
Arginine SCHEMBL27620474 0.87 ALOX15 (0.36) —
Arginine SCHEMBL27611401 0.87 PTH1R (0.36) GLP1R
Tyrosine SCHEMBL27660428 0.85 IL23R (0.36) GLP1RSCTR
Arginine SCHEMBL27730473 0.84 GLP1R (0.34) GLP1RSCTRKLK7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1562579-A1 THERAPEUTIC DELIVERY OF CARBON MONOXIDE Hemocorm Limited (GB) 2005-08-17 — — EP claimed
WO-2004045599-A1 THERAPEUTIC DELIVERY OF CARBON MONOXIDE HEMOCORM LIMITED (GB) 2004-06-03 — — WO claimed