SCHEMBL4587222

SCHEMBL4587222

CC(C)OC(=O)CN(C)C(=N)N

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 1/20 0.42
ITGA2B P08514 1/20 0.42
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
NOS2 P35228 1/20 0.39
LMNA P02545 2/20 0.36
CA1 P00915 12/20 0.35
CA2 P00918 12/20 0.35
TSHR P16473 2/20 0.34
F2 P00734 1/20 0.33
F10 P00742 1/20 0.33
PRSS1 P07477 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA4 P43681 1/20 0.32
CA12 O43570 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13850904 0.89 NOS3 (0.39) ITGB3ITGA2BNOS3NOS1NOS2
SCHEMBL4093905 0.83 NOS3 (0.45) ITGB3ITGA2BNOS3NOS1NOS2
SCHEMBL19670823 0.81 MAPT (0.40) ITGB3ITGA2BNOS3NOS1NOS2
SCHEMBL25515864 0.81 CA1 (0.34) ITGB3ITGA2BNOS3NOS1NOS2
SCHEMBL16540241 0.81 NOS3 (0.37) ITGB3ITGA2BNOS3NOS1NOS2
SCHEMBL18119733 0.80 NOS3 (0.46) ITGB3ITGA2BNOS3NOS1NOS2
SCHEMBL18119735 0.80 NOS3 (0.36) ITGB3ITGA2BNOS3NOS1NOS2
SCHEMBL18121928 0.80 NOS3 (0.43) ITGB3ITGA2BNOS3NOS1NOS2
SCHEMBL3812152 0.79 NOS3 (0.39) NOS3NOS1NOS2CA1CA2
SCHEMBL13850903 0.79 ALDH1A1 (0.39) NOS3NOS1NOS2LMNACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080254198-A1 Method of Preparing Creatine Ester Salts and Uses Thereof BIO-ENGINEERED SUPPLEMENTS & NUTRITION, INC. (US) 2008-10-16 US claimed