Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.50 |
| ▸ | MAP3K7 | O43318 | 7/20 | 0.50 |
| ▸ | MAP4K2 | Q12851 | 7/20 | 0.50 |
| ▸ | LYN | P07948 | 3/20 | 0.49 |
| ▸ | SRC | P12931 | 3/20 | 0.49 |
| ▸ | INSR | P06213 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | HCK | P08631 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.47 |
| ▸ | CSK | P41240 | 4/20 | 0.47 |
| ▸ | MAP3K20 | Q9NYL2 | 4/20 | 0.47 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | RAF1 | P04049 | 2/20 | 0.47 |
| ▸ | EPHB2 | P29323 | 2/20 | 0.47 |
| ▸ | ABL2 | P42684 | 2/20 | 0.47 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14097854 | 0.92 | MAPK14 (0.47) | CSF1RMAPK14MAP3K7MAP4K2LYN | |
| SCHEMBL4587727 | 0.91 | INSR (0.59) | CSF1RMAPK14MAP3K7MAP4K2LYN | |
| SCHEMBL4588859 | 0.86 | MAPK14 (0.67) | MAPK14MAP3K7MAP4K2LYNSRC | |
| SCHEMBL13269773 | 0.86 | LYN (0.62) | CSF1RLYNSRCINSRLCK | |
| SCHEMBL14097772 | 0.85 | LYN (0.48) | MAPK14MAP3K7MAP4K2LYNSRC | |
| SCHEMBL3234488 | 0.84 | CSF1R (0.60) | CSF1RMAPK14MAP3K7MAP4K2LYN | |
| SCHEMBL4586326 | 0.84 | LYN (0.58) | CSF1RMAPK14MAP3K7MAP4K2LYN | |
| SCHEMBL4586222 | 0.84 | PIKFYVE (0.57) | CSF1RLYNSRCINSRLCK | |
| SCHEMBL14097853 | 0.83 | MAPK14 (0.54) | MAPK14MAP3K7MAP4K2LYNSRC | |
| SCHEMBL4588254 | 0.82 | BRAF (0.59) | CSF1RMAPK14MAP3K7MAP4K2LYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188483-A1 | Compounds and Compositions as Protein Kinase Inhibitors | IRM LLC (BM) | 2008-08-07 | — | — | US | claimed |
| EP-1858521-A2 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHBITORS | IRM, LLC (BM) | 2007-11-28 | — | — | EP | claimed |
| WO-2006101783-A2 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2006-09-28 | — | — | WO | claimed |
| US-20080188483-A1 | Compounds and Compositions as Protein Kinase Inhibitors | IRM LLC (BM) | 2008-08-07 | — | — | US | disclosed |
| US-20080188483-A1 | Compounds and Compositions as Protein Kinase Inhibitors | IRM LLC (BM) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188483-A1 | Compounds and Compositions as Protein Kinase Inhibitors | SRC, SGK2, PTK2B | CSF1R 788/4885MAPK14 260/4885MAP3K7 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.