SCHEMBL458808

SCHEMBL458808

C=CCOC(=O)NCCCC[C@H](N)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DDAH1 O94760 2/20 0.52
OTC P00480 1/20 0.42
GSR P00390 1/20 0.42
DPP7 Q9UHL4 3/20 0.40
DPP8 Q6V1X1 2/20 0.40
ARG2 P78540 4/20 0.39
ARG1 P05089 3/20 0.39
ANPEP P15144 1/20 0.39
SLC1A3 P43003 1/20 0.38
SLC1A1 P43005 1/20 0.38
DPP4 P27487 1/20 0.38
DPP9 Q86TI2 1/20 0.38
TGM2 P21980 1/20 0.37
ERN1 O75460 1/20 0.36
NOD1 Q9Y239 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30033086 1.00 DDAH1 (0.52) DDAH1OTCGSRDPP7DPP8
SCHEMBL9966613 1.00 DDAH1 (0.52) DDAH1OTCGSRDPP7DPP8
Hydrochloric Acid SCHEMBL30096368 0.99 DDAH1 (0.51) DDAH1OTCGSRDPP7DPP8
SCHEMBL7194971 0.95 DDAH1 (0.57) DDAH1OTCGSRDPP7DPP8
SCHEMBL22281180 0.95 DDAH1 (0.57) DDAH1OTCGSRDPP7DPP8
SCHEMBL28297586 0.95 DDAH1 (0.57) DDAH1OTCGSRDPP7DPP8
SCHEMBL24185361 0.89 DDAH1 (0.46) DDAH1OTCGSRSLC1A3SLC1A1
SCHEMBL31710914 0.89 DDAH1 (0.53) DDAH1OTCGSRDPP7DPP8
SCHEMBL30310821 0.88 DDAH1 (0.43) DDAH1DPP7DPP8ANPEPDPP4
SCHEMBL24946771 0.88 DDAH1 (0.44) DDAH1OTCGSRDPP7DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018057-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases JANSSEN BIOTECH, INC. (US) 2024-06-25 US claimed
US-20240158735-A1 METHODS AND COMPOSITIONS USING AN ENGINEERED RELEASE FACTOR OXFORD FINANCE LLC, AS COLLATERAL AGENT 2024-05-16 US claimed
CN-116601297-A Modified helicase and application thereof 北京齐碳科技有限公司 2023-08-15 CN claimed
US-20230212535-A1 MODIFIED HELICASES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-07-06 US claimed
EP-4198125-A2 PIF1-LIKE HELICASE AND USE THEREOF Qitan Technology Ltd., Beijing (CN) 2023-06-21 EP claimed
US-20220402983-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES JANSSEN BIOTECH, INC. 2022-12-22 US claimed
US-11525125-B2 Modified helicases OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2022-12-13 US claimed
EP-4063382-A9 PIF1-LIKE HELICASE AND APPLICATION THEREOF Qitan Technology Ltd., Beijing (CN) 2022-11-16 EP claimed
EP-4063382-A1 PIF1-LIKE HELICASE AND APPLICATION THEREOF Qitan Technology Ltd., Beijing (CN) 2022-09-28 EP claimed
US-20220290223-A1 PIF1-LIKE HELICASE AND USE THEREOF Qitan Technology Ltd. (CN) 2022-09-15 US claimed
CN-114599666-A Pif1-like helicase and application thereof 北京齐碳科技有限公司 2022-06-07 CN claimed
CN-113930406-A Pif1-like helicase and application thereof 北京齐碳科技有限公司 2022-01-14 CN claimed
CN-105899678-A Modified enzymes 牛津纳米孔技术公司 2016-08-24 CN claimed
US-6590061-B1 Synthetic polypeptide or peptides having narrow molecular weight distribution used as telechelic polymers for synthesis of block or graft copolymers INSTITUTE OF MACROMOLECULAR CHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 2003-07-08 US claimed
EP-1088020-B1 FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF USTAV MAKROMOLEKULARNI CHEMIE (CZ) 2002-12-18 EP claimed
EP-1088020-A1 FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF USTAV MAKROMOLEKULARNI CHEMIE AKADEMIE VED CESKE REPUBLIKY (CZ) 2001-04-04 EP claimed
WO-1999064495-A1 FUNCTIONALISED POLYMERS OF α-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY (CZ) 1999-12-16 WO claimed
CN-122036912-A Cytokine conjugates for the treatment of proliferative and infectious diseases 辛索克斯公司 2026-05-15 CN disclosed
EP-1088020-A1 FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF USTAV MAKROMOLEKULARNI CHEMIE AKADEMIE VED CESKE REPUBLIKY (CZ) 2001-04-04 EP disclosed
WO-1999064495-A1 FUNCTIONALISED POLYMERS OF α-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY (CZ) 1999-12-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402983-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL1RN, VIP DDAH1 3874/4885OTC 4590/4885GSR 3905/4885
US-12018057-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases IL23R, IL1RN, VIP DDAH1 3874/4885OTC 4590/4885GSR 3905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.