SCHEMBL22281180

SCHEMBL22281180

C=CCOC(=O)NCCC[C@@H](N)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDAH1 O94760 2/20 0.57
OTC P00480 1/20 0.47
GSR P00390 1/20 0.40
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39
SLC1A3 P43003 1/20 0.39
SLC1A1 P43005 1/20 0.39
ARG2 P78540 4/20 0.37
ARG1 P05089 3/20 0.37
DPP8 Q6V1X1 1/20 0.36
DPP7 Q9UHL4 1/20 0.36
GRIK1 P39086 2/20 0.36
GRIK2 Q13002 2/20 0.36
CYP1A2 P05177 1/20 0.36
GLA P06280 1/20 0.36
TSHR P16473 1/20 0.36
NFKB1 P19838 1/20 0.36
APEX1 P27695 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28297586 1.00 DDAH1 (0.57) DDAH1OTCGSRMEN1GAA
SCHEMBL7194971 1.00 DDAH1 (0.57) DDAH1OTCGSRMEN1GAA
SCHEMBL9966613 0.95 DDAH1 (0.52) DDAH1OTCGSRSLC1A3SLC1A1
SCHEMBL458808 0.95 DDAH1 (0.52) DDAH1OTCGSRSLC1A3SLC1A1
SCHEMBL30033086 0.95 DDAH1 (0.52) DDAH1OTCGSRSLC1A3SLC1A1
Hydrochloric Acid SCHEMBL30096368 0.94 DDAH1 (0.51) DDAH1OTCGSRSLC1A3SLC1A1
SCHEMBL24185361 0.91 DDAH1 (0.46) DDAH1OTCGSRKMT2ASLC1A3
SCHEMBL22281181 0.87 DDAH1 (0.43) DDAH1MEN1GAAKMT2ADPP8
SCHEMBL10078341 0.84 DDAH1 (0.41) DDAH1MEN1GAAKMT2ADPP7
SCHEMBL16093029 0.84 DDAH1 (0.41) DDAH1MEN1GAAKMT2ADPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109847107-B Medical artificial joint material and preparation method thereof 湖南博隽生物医药有限公司 2021-09-03 CN claimed
CN-109837090-B Saline-alkali soil remediation method 广东宜瑞环境科技有限公司 2021-04-20 CN claimed
CN-112402698-A Antioxidant wear-resistant medical artificial joint material 湖南博隽生物医药有限公司 2021-02-26 CN claimed
CN-109847107-A Medical artificial joint material and preparation method thereof 湖南博隽生物医药有限公司 2019-06-07 CN claimed
CN-109845898-A A kind of additive for farm animal feed and preparation method thereof 朱美 2019-06-07 CN claimed
CN-109837090-A A kind of restorative procedure of salt affected soil 广东宜瑞环境科技有限公司 2019-06-04 CN claimed
US-11231424-B2 Levetiracetam immunoassays ARK DIAGNOSTICS, INC. (US) 2022-01-25 US disclosed
CN-109847107-B Medical artificial joint material and preparation method thereof 湖南博隽生物医药有限公司 2021-09-03 CN disclosed
CN-109837090-B Saline-alkali soil remediation method 广东宜瑞环境科技有限公司 2021-04-20 CN disclosed
CN-112402698-A Antioxidant wear-resistant medical artificial joint material 湖南博隽生物医药有限公司 2021-02-26 CN disclosed
US-20200240991-A1 Levetiracetam Immunoassays ARES CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT 2020-07-30 US disclosed
CN-109847107-A Medical artificial joint material and preparation method thereof 湖南博隽生物医药有限公司 2019-06-07 CN disclosed
CN-109845898-A A kind of additive for farm animal feed and preparation method thereof 朱美 2019-06-07 CN disclosed
CN-109845898-A A kind of additive for farm animal feed and preparation method thereof 朱美 2019-06-07 CN disclosed
CN-109837090-A A kind of restorative procedure of salt affected soil 广东宜瑞环境科技有限公司 2019-06-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200240991-A1 Levetiracetam Immunoassays GABRG1, GABRA6, LY96 DDAH1 2803/4885OTC 298/4885GSR 2135/4885
US-11231424-B2 Levetiracetam immunoassays GABRG1, GABRA6, LY96 DDAH1 2803/4885OTC 298/4885GSR 2135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.