Cyclohexane

Cyclohexane

SCHEMBL458810

C1CCCCC1.CCCC(=O)O

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.81
HDAC3 O15379 1/20 0.81
HDAC1 Q13547 1/20 0.81
HDAC2 Q92769 1/20 0.81
HDAC8 Q9BY41 1/20 0.81
AKR1B1 P15121 1/20 0.52
GPR84 Q9NQS5 7/20 0.50
PPARG P37231 7/20 0.50
PPARD Q03181 7/20 0.50
PPARA Q07869 7/20 0.50
HDAC11 Q96DB2 5/20 0.50
TSHR P16473 4/20 0.50
PTPN1 P18031 3/20 0.50
ALDH1A1 P00352 2/20 0.50
TLR2 O60603 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
FABP4 P15090 2/20 0.50
KMT2A Q03164 2/20 0.50
SLC22A6 Q4U2R8 1/20 0.50
SLC22A8 Q8TCC7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL16341925 1.00 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8
Cyclohexane SCHEMBL7426842 1.00 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL11348636 1.00
Cyclohexane SCHEMBL27815810 1.00 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL3509473 1.00 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8
Cyclohexane SCHEMBL3364580 1.00 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8
Cyclohexane SCHEMBL9778100 0.97 FFAR3 (0.77) FFAR3HDAC3HDAC1HDAC2HDAC8
Cyclohexane SCHEMBL2800628 0.97 FFAR3 (0.77) FFAR3HDAC3HDAC1HDAC2HDAC8
Cyclohexane SCHEMBL1316440 0.97 FFAR3 (0.77) FFAR3HDAC3HDAC1HDAC2HDAC8
Cyclohexane SCHEMBL3247017 0.97 FFAR3 (0.77) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 874 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118834397-A Two-dimensional reticular non-fully conjugated metal-supermolecular polymer and preparation method and application thereof 河南大学 2024-10-25 CN claimed
CN-118754842-A Tryptophan derivative and preparation method and application thereof 中国人民解放军北部战区总医院 2024-10-11 CN claimed
CN-118206774-A Non-fully conjugated metal-supermolecular polymer and preparation method and application thereof 河南大学 2024-06-18 CN claimed
US-20240051907-A1 CATALYST SYSTEM SYMRISE AG (DE) 2024-02-15 US claimed
EP-4247553-A2 CATALYST SYSTEM COMPRISING ZINC CARBOXYLATE OR COBALT CARBOXYLATE AND AMINOPHENOLS, AND USE THEREOF Symrise AG (DE) 2023-09-27 EP claimed
WO-2021151790-A2 CATALYST SYSTEM SYMRISE AG (DE) 2021-08-05 WO claimed
EP-3625301-A1 CHLOROPRENE ADHESIVE SYSTEM Rema Tip Top AG (DE) 2020-03-25 EP claimed
CN-110218578-A Use the method and system of catalytic hydrocracking and hot coking upgrading heavy oil 源之重油有限公司 2019-09-10 CN claimed
WO-2018211019-A1 CHLOROPRENE ADHESIVE SYSTEM REMA TIP TOP AG (DE) 2018-11-22 WO claimed
CN-105181403-B Single element standard oil and preparation method thereof 中国兵器工业集团第五三研究所 2018-02-09 CN claimed
CN-1824315-A Synergistic therapeutic compositions and methods PFIZER (US) 2006-08-30 CN claimed
CN-1263404-C Ambient stable beverage UNILEVER NV (NL) 2006-07-12 CN claimed
CN-1784454-A Electroluminescent metal-supramolecules with terpyridine-based groups UNIV HONG KONG (HK) 2006-06-07 CN claimed
CN-1724532-A Colorant compound XEROX CORP (US) 2006-01-25 CN claimed
CN-1724597-A Phase change inks XEROX CORP (US) 2006-01-25 CN claimed
CN-1211330-C Method for preparing halogenated hydrocarbons SOLVAY (BE) 2005-07-20 CN claimed
CN-1443043-A Ambient stable beverage UNILEVER NV (NL) 2003-09-17 CN claimed
CN-1429079-A Ambient stable beverage UNILEVER NV (NL) 2003-07-09 CN claimed
WO-2001057923-A1 METHOD FOR PRODUCING ELECTRICAL CONNECTIONS IN PARTICULAR FOR AN ELECTRONIC DEVICE GEMPLUS (FR) 2001-08-09 WO claimed
US-5491178-A STABILIZING, INHIBITING THE DEHYDROGENATION BY APPLYING A COATING MIXTURE COMPRISING HINDERED PHENOLS, ORGANIC SULFIDES OR DISULFIDES AND TRANSITION METAL SALTS OR COMPLEXES ALLIEDSIGNAL INC. (US) 1996-02-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240051907-A1 CATALYST SYSTEM GYS2, HSD17B4, PAOX FFAR3 149/4885HDAC3 574/4885HDAC1 546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.