SCHEMBL458902

SCHEMBL458902

CCc1c[c]cc(F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17046404 0.82 CNR1 (0.32)
SCHEMBL297355 0.82 TP53 (0.36)
SCHEMBL7670959 0.79 HTT (0.38)
SCHEMBL27568249 0.76
SCHEMBL17046385 0.76
SCHEMBL28203687 0.76
SCHEMBL17046270 0.76 GABRA1 (0.33)
SCHEMBL27705918 0.74 LOXL2 (0.41)
SCHEMBL27758806 0.74 LOXL2 (0.41)
SCHEMBL15939372 0.74 FFAR1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3615527-B1 NEW AZAQUINOLINE DERIVATIVES ELANCO ANIMAL HEALTH GMBH (DE) 2024-03-06 EP disclosed
CN-110770227-B Novel azaquinoline derivatives 拜耳动物保健有限责任公司 2024-03-01 CN disclosed
US-20230174492-A1 SUBSTITUTED CONDENSED AZINES AS ANTHELMINTIC COMPOUNDS ELANCO ANIMAL HEALTH GMBH (DE) 2023-06-08 US disclosed
CN-110536892-B Novel bicyclic pyrazole derivatives 拜耳动物保健有限责任公司 2023-05-12 CN disclosed
EP-4132911-A1 SUBSTITUTED CONDENSED AZINES AS ANTHELMINTIC COMPOUNDS Bayer Animal Health GmbH (DE) 2023-02-15 EP disclosed
CN-115667221-A Substituted fused oxazines as insect repellent compounds 拜耳动物保健有限责任公司 2023-01-31 CN disclosed
US-11485733-B2 Azaquinoline derivatives BAYER ANIMAL HEALTH GMBH (DE) 2022-11-01 US disclosed
US-11130768-B2 Bicyclic pyrazole derivatives BAYER ANIMAL HEALTH GMBH (DE) 2021-09-28 US disclosed
CN-108352572-B Additive for nonaqueous electrolyte solution, and electricity storage device 住友精化株式会社 2021-02-02 CN disclosed
EP-3373379-B1 ADDITIVE FOR NONAQUEOUS ELECTROLYTE SOLUTIONS, NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTRICITY STORAGE DEVICE SUMITOMO SEIKA CHEMICALS (JP) 2020-10-21 EP disclosed
CN-101952279-A Azolylmethyloxiranes, use thereof and agents containing the same BASF SE 2011-01-19 CN disclosed
CN-101945580-A Azolylmethyloxiranes, use thereof and compositions comprising them BASF SE 2011-01-12 CN disclosed
US-20100317515-A1 Azolylmethyloxiranes, use Thereof and Agents Containing the Same BASF SE (DE) 2010-12-16 US disclosed
US-20100311581-A1 Azolylmethyloxiranes, use Thereof and Agents Containing the Same BASF SE (DE) 2010-12-09 US disclosed
CN-101902914-A Azolylmethyloxiranes, use thereof and compositions comprising same BASF SE 2010-12-01 CN disclosed
US-20100273651-A1 Azolylmethyloxiranes, use Thereof and Agents Containing the Same BASF SE (DE) 2010-10-28 US disclosed
EP-2234488-A2 AZOLYLMETHYLOXIRANES, USE THEREOF AND AGENTS CONTAINING THE SAME BASF SE (DE) 2010-10-06 EP disclosed
CN-101506166-A Substituted 1-(azolin-2-yl)-amino-2-aryl-1-hetaryl-ethane compounds BASF SE (DE) 2009-08-12 CN disclosed
WO-2009077443-A2 AZOLYLMETHYLOXIRANES, USE THEREOF AND AGENTS CONTAINING THE SAME BASF SE (DE) 2009-06-25 WO disclosed
US-20090131256-A1 Substituted 1-(azolin-2-yl)-amino-2-aryl-1-hetaryl-ethane Compounds BASF SE (DE) 2009-05-21 US disclosed