⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27650510 | 0.97 | — | — | |
| SCHEMBL7610680 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL7616783 | 0.90 | ALDH1A1 (0.46) | — | |
| SCHEMBL896820 | 0.83 | — | — | |
| SCHEMBL1837224 | 0.83 | KDM4E (0.48) | — | |
| SCHEMBL1309431 | 0.83 | TDP1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL27491583 | 0.81 | — | — | |
| SCHEMBL1839119 | 0.80 | KDM4E (0.52) | — | |
| SCHEMBL1837168 | 0.80 | KDM4E (0.52) | — | |
| SCHEMBL11173620 | 0.80 | KDM4E (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052879-B | Compounds consisting of C20 modified salinomycin derivatives, process for obtaining them, compositions comprising them, use of the compounds and process for obtaining intermediates | 菲莱克洛有限责任公司 | 2024-05-10 | — | — | CN | disclosed |
| EP-4100411-B1 | COMPOUNDS CONSTITUTING C20-MODIFIED SALINOMYCIN DERIVATIVES, A METHOD FOR OBTAINING THE SAME, A COMPOSITION CONTAINING THE SAME, A USE OF SAID COMPOUNDS AND A METHOD FOR OBTAINING AN INTERMEDIATE PRODUCT | FILECLO SP Z O O (PL) | 2023-08-16 | — | — | EP | disclosed |
| US-20220402932-A1 | Compounds Constituting C20-Modified Salinomycin Derivatives, a Method for Obtaining the Same, a Composition Containing the Same, a Use of Said Compounds and a Method for Obtaining an Intermediate Product | FILECLO SP. Z O.O. (PL) | 2022-12-22 | — | — | US | disclosed |
| EP-4100411-A1 | COMPOUNDS CONSTITUTING C20-MODIFIED SALINOMYCIN DERIVATIVES, A METHOD FOR OBTAINING THE SAME, A COMPOSITION CONTAINING THE SAME, A USE OF SAID COMPOUNDS AND A METHOD FOR OBTAINING AN INTERMEDIATE PRODUCT | Fileclo Sp. z o.o. (PL) | 2022-12-14 | — | — | EP | disclosed |
| US-20220380320-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING MIDDLE EAST RESPIRATORY SYNDROME | GYEONGGIDO BUSINESS & SCIENCE ACCELERATOR (KR) | 2022-12-01 | — | — | US | disclosed |
| CN-115052879-A | Compound consisting of C20 modified salinomycin derivatives, method for obtaining same, composition comprising same, use of said compound and method for obtaining intermediate product | 菲莱克洛有限责任公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-113876815-A | Application of parabacteroides dieldii in medicine for treating and preventing male reproductive toxicity | 四川大学华西医院 | 2022-01-04 | — | — | CN | disclosed |
| WO-2021156461-A1 | COMPOUNDS CONSTITUTING C20-MODIFIED SALINOMYCIN DERIVATIVES, A METHOD FOR OBTAINING THE SAME, A COMPOSITION CONTAINING THE SAME, A USE OF SAID COMPOUNDS AND A METHOD FOR OBTAINING AN INTERMEDIATE PRODUCT | FILECLO SP. Z O.O. (PL) | 2021-08-12 | — | — | WO | disclosed |
| CN-111741760-A | Compositions and methods for neurological disorders | 科达生物治疗医药有限公司 | 2020-10-02 | — | — | CN | disclosed |
| WO-2020159343-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING MIDDLE EAST RESPIRATORY SYNDROME | 재단법인 경기도경제과학진흥원 | 2020-08-06 | — | — | WO | disclosed |
| US-6534509-B1 | Derivatives are useful as anti-inflammatory agents. This invention is also directed to pharmacetutical compostions for inflammation | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-03-18 | — | — | US | disclosed |
| EP-0988292-B1 | PIPERAZINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | SCHERING AG (DE) | 2003-02-12 | — | — | EP | disclosed |
| US-20020177598-A1 | Piperazine derivatives and their use as anti-inflammatory agents | SCHERING AKTIENGSCHELLSCHAFT | 2002-11-28 | — | — | US | disclosed |
| EP-1254899-A2 | Piperazine derivatives and their use as anti-inflammatory agents | Schering Aktiengesellschaft (DE) | 2002-11-06 | — | — | EP | disclosed |
| US-6207665-B1 | TO TREAT INFLAMMATORY DISORDERS IN HUMANS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-27 | — | — | US | disclosed |
| US-4818271-A | PLANT GROWTH REGULATORS | FMC CORPORATION (US) | 1989-04-04 | — | — | US | disclosed |
| US-4707550-A | N-(substituted thienyl)-N'-(substituted piperazinyl)-ureas | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |
| EP-0244176-A2 | Thienopyrimidine-2,4-dione derivatives and intermediates thereof | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-11-04 | — | — | EP | disclosed |
| US-4670560-A | VASODILATING AGENTS, HYPOTENSIVE AGENTS AND/OR CARDIOVASCULAR AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-06-02 | — | — | US | disclosed |
| US-4315020-A | Oxazoline (trifluoroethyl) amine | SCIENCE UNION ET CIE (FR) | 1982-02-09 | — | — | US | disclosed |