SCHEMBL896820

SCHEMBL896820

NC(=O)NCCCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27491583 0.97
SCHEMBL27862400 0.92 TSHR (0.36)
Alcohol SCHEMBL28291143 0.90 FAAH (0.44)
Propyne SCHEMBL28961113 0.86 FAAH (0.37)
SCHEMBL4589029 0.83
Hydrochloric Acid SCHEMBL27650510 0.81
SCHEMBL7610680 0.81
SCHEMBL175234 0.81 TDP1 (0.46)
Hydrochloric Acid SCHEMBL7616783 0.79 ALDH1A1 (0.46)
SCHEMBL2914921 0.78 LMNA (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 409 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720072-A2 RAS INHIBITORS Revolution Medicines, Inc. (US) 2026-04-08 EP claimed
US-20260078133-A1 RAS INHIBITORS Revolution Medicines, Inc. 2026-03-19 US claimed
EP-4688790-A1 MACROCYCLIC RAS INHIBITORS Revolution Medicines, Inc. (US) 2026-02-11 EP claimed
US-20260028353-A1 MACROCYCLIC RAS INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2026-01-29 US claimed
CN-115873020-B RAS inhibitors 锐新医药公司 2025-06-13 CN claimed
US-12252497-B2 Ras inhibitors Revolution Medicines, Inc. (US) 2025-03-18 US claimed
US-20250051306-A1 RAS INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT 2025-02-13 US claimed
CN-119192619-A Carboxymethyl cellulose starch ether for cleaning photovoltaic panel and preparation method and application thereof 河北业之源新材料股份有限公司 2024-12-27 CN claimed
WO-2024249299-A2 RAS INHIBITORS Revolution Medicines, Inc. (US) 2024-12-05 WO claimed
CN-118852330-A RAS inhibitors for the treatment of cancer 锐新医药公司 2024-10-29 CN claimed
US-20060127337-A1 Process for relaxing keratin fibres L'OREAL (FR) 2006-06-15 US claimed
EP-1661551-A2 Method of straightening keratin fibres with heating means and a denaturant agent L'OREAL (FR) 2006-05-31 EP claimed
US-5593970-A ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING BIOCHEM PHARMA INC. (CA) 1997-01-14 US claimed
EP-0659190-A1 ANTINEOPLASTIC HETERONAPHTHOQUINONES BIOCHEM PHARMA INC (CA) 1995-06-28 EP claimed
WO-1995012588-A1 ANTINEOPLASTIC HETERONAPHTHOQUINONES BIOCHEM PHARMA INC. (CA) 1995-05-11 WO claimed
CN-1094402-A Antineoplastic heteronaphthoquinones IAF BIOCHEM INT (CA) 1994-11-02 CN claimed
WO-1994011382-A1 ANTINEOPLASTIC HETERONAPHTHOQUINONES BIOCHEM PHARMA INC. (CA) 1994-05-26 WO claimed
CN-86107258-A Pyridyl carbamide compound and on agricultural, using 1987-05-27 CN claimed
EP-0067019-B1 NOVEL NITROSOUREA COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Kimura, Goro (JP) 1986-03-19 EP claimed
EP-0067019-A1 Novel nitrosourea compound, method for preparing same, and pharmaceutical composition containing same Kimura, Goro (JP) 1982-12-15 EP claimed