Pyridine

Pyridine

SCHEMBL4589055

C1CN2CCN1CC2.c1ccncc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.60
NAPRT Q6XQN6 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
MAPT P10636 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CHKA P35790 1/20 0.31
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL2544321 0.81 TSHR (0.45) TSHRNAPRTTDP1MAPTNPSR1
Pyridine SCHEMBL9577788 0.80 TSHR (0.60) TSHRNAPRTTDP1MAPTNPSR1
Methenamine SCHEMBL28834492 0.80 TSHR (0.60) TSHRNAPRTTDP1NOTUM
SCHEMBL3052767 0.78 TSHR (1.00) TSHRNAPRTTDP1MAPTNOTUM
Pyridine SCHEMBL16 0.78
Benzene SCHEMBL10751789 0.78 TSHR (1.00) TSHRNAPRTTDP1MAPTNOTUM
Pyridine SCHEMBL933604 0.78 TSHR (1.00) TSHRNAPRTTDP1MAPTNOTUM
Pyridine SCHEMBL9037865 0.78 TSHR (1.00) TSHRNAPRTTDP1MAPTNOTUM
Benzene SCHEMBL1261317 0.78 TSHR (1.00) TSHRNAPRTTDP1MAPTNOTUM
Pyridine SCHEMBL1654468 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677443-B Method for constructing 1, 4-diketone compound by olefin 1, 2-dicarbonylation 中国科学院理化技术研究所 2024-07-16 CN claimed
US-7459470-B2 N-oxide anthranylamide derivatives and their use as medicaments SCHERING AG (DE) 2008-12-02 US disclosed
US-7429592-B2 Cyanoanthranilamide derivatives and the use thereof as medicaments SCHERING AKTIENEGESELLSCHAFT (DE) 2008-09-30 US disclosed
CN-1309704-C Anthranilic acid amides and their use as medicaments SCHERING AG (DE) 2007-04-11 CN disclosed
US-7012081-B2 Anthranyl amides and their use as medicaments SCHERING AG (DE) 2006-03-14 US disclosed
US-20050261343-A1 Anthranilamides and their use as pharmaceutical agents BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2005-11-24 US disclosed
US-20050032816-A1 N-oxide anthranylamide derivatives and their use as medicaments BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2005-02-10 US disclosed
US-20040266770-A1 Cyanoanthranilamide derivatives and the use thereof as medicaments BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2004-12-30 US disclosed
US-20040029880-A1 Anthranyl amides and their use as medicaments BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2004-02-12 US disclosed
CN-1429200-A Anthranilic acid amides and their use as medicaments SCHERING AG (DE) 2003-07-09 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050261343-A1 Anthranilamides and their use as pharmaceutical agents AADAC, ANTXR2, VEGFA TSHR 3635/4885NAPRT 200/4885TDP1 4664/4885
US-20050032816-A1 N-oxide anthranylamide derivatives and their use as medicaments FLT4, KDR, NOS3 TSHR 2967/4885NAPRT 1179/4885TDP1 4181/4885
US-20040029880-A1 Anthranyl amides and their use as medicaments AADAC, ANTXR2, VEGFA TSHR 3677/4885NAPRT 164/4885TDP1 4810/4885
US-20040266770-A1 Cyanoanthranilamide derivatives and the use thereof as medicaments FLT4, KDR, FLT1 TSHR 2690/4885NAPRT 2040/4885TDP1 3724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.