Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.63 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PAM | P19021 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838112 | 0.94 | DGKA (0.73) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL7839076 | 0.92 | DGKA (0.77) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL8893920 | 0.92 | DGKA (0.77) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL8893739 | 0.92 | DGKA (0.77) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL8894559 | 0.92 | DGKA (0.77) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL7829125 | 0.92 | DGKA (0.77) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL938867 | 0.92 | DGKA (0.77) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL3502039 | 0.92 | DGKA (0.77) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL5387189 | 0.92 | DGKA (0.77) | DGKADNM1PRSS1PRSS2PRSS3 | |
| SCHEMBL5385058 | 0.92 | DGKA (0.77) | DGKADNM1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4818754-A | ANTIALLERGENS | BEECHAM GROUP P.L.C. OF BEECHAM HOUSE (GB) | 1989-04-04 | — | — | US | claimed |
| EP-0243055-A2 | Pyrazolopyridine derivatives, process for their preparation, and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-10-28 | — | — | EP | claimed |
| WO-2008047883-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-04-24 | — | — | WO | disclosed |
| US-6339162-B1 | SOLVOLYSIS OF 4-ACETYLOXYPHENYL-ACETYL-.BETA.-D-GLUCOPYRANOSIDE DERIVATIVE, NEUTRALIZATION WITH ACID, CRYSTALLIZATION OF ARBUTIN OR ITS DERIVATIVE | NISSHIN PHARMA INC. (JP) | 2002-01-15 | — | — | US | disclosed |
| EP-0751133-B1 | Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same | MITSUI CHEMICALS INC (JP) | 2001-09-12 | — | — | EP | disclosed |
| EP-1043321-A1 | Process for the preparation of tetrahydropyran derivatives | Nisshin Flour Milling Co., Ltd. (JP) | 2000-10-11 | — | — | EP | disclosed |
| EP-0601439-B1 | Dye mixtures containing dyes with a coupling component of the diaminopyridine type | BASF AG (DE) | 1999-07-07 | — | — | EP | disclosed |
| US-5770108-A | HIGH SPEED RESPONSE, MOLECULAR ORIENTATION, HIGH CONTRAST, RECEPTIVITY | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-06-23 | — | — | US | disclosed |
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |
| EP-0751133-A1 | Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1997-01-02 | — | — | EP | disclosed |
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |
| US-5403363-A | Applying to textile material for printing and dyeing; colorfastness | BASF AKTIENGESELLSCHAFT (DE) | 1995-04-04 | — | — | US | disclosed |
| EP-0601439-A2 | Dye mixtures containing dyes with a coupling component of the diaminopyridine type | BASF Aktiengesellschaft (DE) | 1994-06-15 | — | — | EP | disclosed |
| US-5162045-A | Azo Dyes with a Cyanothiophene Group | BASF AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | disclosed |
| US-5069991-A | NAPHTHOLACTAM OR ISINDOLENINE DYE | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| US-4999026-A | Transferring dyes for thermal printing: tri-cyano-vinyl aniline dyes | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0258856-B1 | DYE TRANSFER METHOD | BASF Aktiengesellschaft (DE) | 1990-11-14 | — | — | EP | disclosed |
| US-4906541-A | Electrophotographic recording element containing a naphtholactam dye sensitizer | BASF AKTIENGESELLSCHAFT (DE) | 1990-03-06 | — | — | US | disclosed |
| US-4818754-A | ANTIALLERGENS | BEECHAM GROUP P.L.C. OF BEECHAM HOUSE (GB) | 1989-04-04 | — | — | US | disclosed |
| EP-0243055-A2 | Pyrazolopyridine derivatives, process for their preparation, and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-10-28 | — | — | EP | disclosed |