⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3991516 | 0.64 | CYP2A6 (0.31) | — | |
| SCHEMBL462176 | 0.64 | CYP2A6 (0.31) | — | |
| SCHEMBL7600 | 0.64 | — | — | |
| SCHEMBL12430552 | 0.61 | ALDH1A1 (0.35) | — | |
| SCHEMBL18929048 | 0.59 | — | — | |
| SCHEMBL24465885 | 0.58 | UHRF1 (0.32) | — | |
| SCHEMBL23181732 | 0.58 | CCR1 (0.32) | — | |
| SCHEMBL23785125 | 0.57 | — | — | |
| SCHEMBL13750085 | 0.57 | — | — | |
| Biphenyl SCHEMBL6297474 | 0.56 | ALDH1A1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 593 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864088-A | The preparation method of novel isoquinoline drug molecule with antibacterial activity | 河南湾流生物科技有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-101311176-A | Isoquinoline compounds, preparation method and use thereof | SHANGHAI INST MATERIA MEDICA (CN) | 2008-11-26 | — | — | CN | claimed |
| US-12611461-B2 | Bioorthogonal compositions | TAMBO, INC. (US) | 2026-04-28 | — | — | US | disclosed |
| US-12600726-B2 | Antagonists of the muscarinic acetylcholine receptor M4 | VANDERBILT UNIVERSITY (US) | 2026-04-14 | — | — | US | disclosed |
| EP-4208564-B1 | NUCLEIC ACID MODIFYING REAGENTS AND USES THEREOF | PROMEGA CORP (US) | 2026-04-08 | — | — | EP | disclosed |
| EP-4721762-A2 | MODIFIED POLYAMINE POLYMERS FOR DELIVERY OF BIOMOLECULES INTO CELLS | Promega Corporation (US) | 2026-04-08 | — | — | EP | disclosed |
| US-12589162-B2 | Trans-cyclooctene prodrug of monomethyl auristatin E | TAMBO, INC. (US) | 2026-03-31 | — | — | US | disclosed |
| EP-4713022-A1 | TRANS-CYCLOOCTENE-MODIFIED TARGETED PROTEIN DEGRADER CONJUGATES | Tambo, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| US-12577234-B2 | Antagonists of the muscarinic acetylcholine receptor M4 | VANDERBILT UNIVERSITY (US) | 2026-03-17 | — | — | US | disclosed |
| EP-4704904-A1 | TETRAZINE-BASED TARGETING AGENTS FOR IN VIVO DELIVERY OF A PAYLOAD | Tambo, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| US-12570654-B2 | Nanoluc suicide substrates | PROMEGA CORPORATION (US) | 2026-03-10 | — | — | US | disclosed |
| US-20090233900-A1 | 2-AMINOBENZAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-09-17 | — | — | US | disclosed |
| CN-101311176-A | Isoquinoline compounds, preparation method and use thereof | SHANGHAI INST MATERIA MEDICA (CN) | 2008-11-26 | — | — | CN | disclosed |
| EP-1955697-A1 | 2-AMINOBENZAMIDE DERIVATIVE | Astellas Pharma Inc. (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-7071332-B2 | Indolinone derivatives as protein kinase/phosphatase inhibitors | SUGEN, INC. (US) | 2006-07-04 | — | — | US | disclosed |
| US-20040147586-A1 | Indolinone derivatives as protein kinase/phosphatase inhibitors | SUGEN, INC. | 2004-07-29 | — | — | US | disclosed |
| US-6706709-B2 | TREATING, FOR EXAMPLE, PROLIFERATIVE DISORDERS INCLUDING CANCER | SUGEN, INC. | 2004-03-16 | — | — | US | disclosed |
| EP-1294688-A2 | INDOLINONE DERIVATIVES AS PROTEIN KINASE/PHOSPHATASE INHIBITORS | Sugen, Inc. (US) | 2003-03-26 | — | — | EP | disclosed |
| US-20020052369-A1 | Indolinone derivatives as protein kinase/phosphatase inhibitors | SUGEN, INC. | 2002-05-02 | — | — | US | disclosed |
| WO-2001094312-A2 | INDOLINONE DERIVATIVES AS PROTEIN KINASE/PHOSPHATASE INHIBITORS | SUGEN, INC. (US) | 2001-12-13 | — | — | WO | disclosed |