Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573010 | 0.81 | MTNR1A (0.60) | MTNR1AMTNR1BKDM4ECYP3A4TSHR | |
| SCHEMBL6634146 | 0.81 | HTR2A (0.56) | MTNR1AMTNR1BCYP3A4TSHRHTR2A | |
| Hydrochloric Acid SCHEMBL10598473 | 0.80 | HTR2A (0.54) | MTNR1AMTNR1BCYP3A4TSHRHTR2A | |
| SCHEMBL6634999 | 0.80 | MTNR1A (0.61) | MTNR1AMTNR1BKDM4E | |
| SCHEMBL5449210 | 0.79 | MTNR1A (0.52) | MTNR1AMTNR1BKDM4ECYP3A4TSHR | |
| SCHEMBL6635133 | 0.79 | MTNR1A (0.57) | MTNR1AMTNR1BCYP3A4TSHRHTR2A | |
| SCHEMBL7333206 | 0.78 | HTR2A (0.46) | MTNR1AMTNR1BOPRM1HTR2A | |
| SCHEMBL31554964 | 0.78 | HTR2A (0.46) | MTNR1AMTNR1BOPRM1HTR2A | |
| SCHEMBL6634086 | 0.77 | MTNR1A (0.51) | MTNR1AMTNR1BKDM4ECYP3A4TSHR | |
| SCHEMBL28205819 | 0.77 | MTNR1A (0.51) | MTNR1AMTNR1BKDM4ECYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1386904-B1 | Acenaphthylene derivative, polymer, and antireflection film-forming composition | JSR CORP (JP) | 2008-09-17 | — | — | EP | disclosed |
| US-7037994-B2 | Acenaphthylene derivative, polymer, and antireflection film-forming composition | JSR CORPORATION (JP) | 2006-05-02 | — | — | US | disclosed |
| US-20040034155-A1 | Acenaphthylene derivative, polymer, and antireflection film-forming composition | JSR CORPORATION (JP) | 2004-02-19 | — | — | US | disclosed |
| EP-1386904-A1 | Acenaphthylene derivative, polymer, and antireflection film-forming composition | JSR Corporation (JP) | 2004-02-04 | — | — | EP | disclosed |