SCHEMBL4589972

SCHEMBL4589972

CCN1CCCCC1C(NC(=O)c1cccc(C(F)(F)F)c1Cl)c1ccccc1

nearest known ligand 0.81

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 13/20 0.81
CTSS P25774 3/20 0.49
CTSK P43235 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4588559 0.99 SLC6A9 (0.80) SLC6A9CTSSCTSK
SCHEMBL4245201 0.90 SLC6A9 (1.00) SLC6A9CTSSCTSK
SCHEMBL4245203 0.90 SLC6A9 (1.00) SLC6A9CTSSCTSK
SCHEMBL4589446 0.90 SLC6A9 (1.00) SLC6A9CTSSCTSK
SCHEMBL4588331 0.89 SLC6A9 (0.73) SLC6A9CTSSCTSK
SCHEMBL3533390 0.89 SLC6A9 (0.98) SLC6A9CTSSCTSK
SCHEMBL1689574 0.89 SLC6A9 (0.98) SLC6A9CTSSCTSK
Hydrochloric Acid SCHEMBL4588406 0.89 SLC6A9 (0.98) SLC6A9CTSSCTSK
Hydrochloric Acid SCHEMBL4588412 0.89 SLC6A9 (0.98) SLC6A9CTSSCTSK
Hydrochloric Acid SCHEMBL3533471 0.88 SLC6A9 (0.96) SLC6A9CTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7326722-B2 N-[Phenyl(piperidin-2-yl)methyl]benzamide derivatives, their preparation and their application in therapy SANOFI-AVENTIS (FR) 2008-02-05 US claimed
US-20070197601-A1 Use of N-[Phenyl(piperidin-2-yl)methyl]benzamide derivatives in therapy SANOFI-AVENTIS (FR) 2007-08-23 US claimed
EP-1499589-B1 DERIVATIVES OF N-PHENYL(PIPERIDIN-2-YL)METHYL BENZAMIDE, THE PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS SANOFI AVENTIS (FR) 2007-05-02 EP claimed
EP-1499589-B1 DERIVATIVES OF N-PHENYL(PIPERIDIN-2-YL)METHYL BENZAMIDE, THE PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS SANOFI AVENTIS (FR) 2007-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070197601-A1 Use of N-[Phenyl(piperidin-2-yl)methyl]benzamide derivatives in therapy SLC1A2, SLC1A1, SLC1A5 SLC6A9 53/4885CTSS 3102/4885CTSK 3396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.