Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 18/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17416415 | 0.86 | TTK (0.46) | TTKMAPK14 | |
| SCHEMBL457294 | 0.79 | TTK (0.47) | TTK | |
| SCHEMBL456494 | 0.78 | TTK (0.49) | TTK | |
| SCHEMBL16295889 | 0.78 | TTK (0.64) | TTK | |
| SCHEMBL459013 | 0.76 | TTK (0.48) | TTKCNR1CNR2 | |
| SCHEMBL470208 | 0.76 | TTK (0.66) | TTK | |
| SCHEMBL15555406 | 0.75 | TTK (0.46) | TTKCNR1CNR2 | |
| SCHEMBL456486 | 0.72 | TTK (0.59) | TTK | |
| SCHEMBL455846 | 0.71 | TTK (0.63) | TTK | |
| SCHEMBL458675 | 0.71 | TTK (0.44) | TTKCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614063-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |