Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 6/20 | 0.34 |
| ▸ | CCND1 | P24385 | 6/20 | 0.34 |
| ▸ | CCND2 | P30279 | 6/20 | 0.34 |
| ▸ | CCND3 | P30281 | 6/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27780814 | 0.85 | CDK4 (0.46) | KDM4ECDC7CDK4CCND1CCND2 | |
| SCHEMBL3847343 | 0.79 | CDC7 (0.35) | CDC7SOS2CDK4CCND1CCND2 | |
| SCHEMBL3869532 | 0.78 | SCN7A (0.42) | MEN1KMT2AKDM4EHSD17B10SCN7A | |
| SCHEMBL3839505 | 0.78 | ALDH1A1 (0.39) | MEN1KMT2AKDM4ECDC7HSD17B10 | |
| SCHEMBL28645958 | 0.76 | CDK4 (0.37) | CDK4CCND1CCND2CCND3CCNB2 | |
| SCHEMBL19231460 | 0.76 | CDC7 (0.44) | CDC7SOS2CDK4CCND1CCND2 | |
| Trifluoroacetic Acid SCHEMBL4590390 | 0.71 | JAK3 (0.35) | SCN7ASCN5ASCN2ASCN8AKCNH2 | |
| SCHEMBL23510554 | 0.69 | CDK4 (0.44) | CDC7CDK4CCND1CCND2CCND3 | |
| SCHEMBL27780816 | 0.67 | CDC7 (0.35) | CDC7SOS2 | |
| SCHEMBL21663753 | 0.65 | CDC7 (0.47) | KDM4ECDC7SOS2MAPTSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071964-A1 | NAPHTHYRIDINE BACTERICIDES | ASTRAZENECA AB (SE) | 2008-06-19 | — | — | WO | disclosed |