Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 5/20 | 0.44 |
| ▸ | CCND1 | P24385 | 5/20 | 0.44 |
| ▸ | CCND2 | P30279 | 3/20 | 0.44 |
| ▸ | CCND3 | P30281 | 3/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 12/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 10/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 7/20 | 0.40 |
| ▸ | CDK2 | P24941 | 3/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19231460 | 0.78 | CDC7 (0.44) | CDK4CCND1CCND2CCND3CDC7 | |
| SCHEMBL29310486 | 0.74 | ADORA2B (0.38) | — | |
| SCHEMBL20710553 | 0.72 | CDK4 (0.45) | CDK4CCND1CCND2CCND3AURKA | |
| SCHEMBL27780816 | 0.72 | CDC7 (0.35) | CDC7NQO1 | |
| SCHEMBL27780814 | 0.72 | CDK4 (0.46) | CDK4CCND1CCND2CCND3CDK2 | |
| SCHEMBL20710534 | 0.71 | MAPK8 (0.47) | CDK4CCND1CCND2CCND3AURKA | |
| SCHEMBL24856132 | 0.71 | CDK4 (0.57) | CDK4CCND1CCND2CCND3AURKA | |
| SCHEMBL27250199 | 0.70 | CDK4 (0.49) | CDK4CCND1CCND2CCND3AURKA | |
| SCHEMBL25463635 | 0.69 | CDK4 (0.58) | CDK4CCND1CCND2CCND3AURKA | |
| SCHEMBL4590556 | 0.69 | MEN1 (0.38) | CDK4CCND1CCND2CCND3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210179636-A1 | ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2021-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210179636-A1 | ANTIBACTERIAL COMPOUNDS | OXA1L, SYMPK, TBCD | CDK4 485/4885CCND1 333/4885CCND2 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.