Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 8/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590727 | 0.87 | HRH3 (0.42) | HRH3MEN1KMT2A | |
| SCHEMBL4590580 | 0.86 | FGFR1 (0.51) | AVPR1BHRH3MEN1KMT2A | |
| SCHEMBL4590224 | 0.86 | KCNA5 (0.40) | HRH3MEN1KMT2AKCNA5 | |
| SCHEMBL4590225 | 0.86 | KCNA5 (0.40) | HRH3MEN1KMT2AKCNA5 | |
| SCHEMBL4590221 | 0.86 | KCNA5 (0.40) | HRH3MEN1KMT2AKCNA5 | |
| SCHEMBL4590572 | 0.86 | HRH3 (0.44) | HRH3MEN1KMT2A | |
| SCHEMBL4591346 | 0.84 | HRH3 (0.42) | HRH3MEN1KMT2A | |
| SCHEMBL4590339 | 0.82 | HRH3 (0.46) | AVPR1BHRH3MEN1KMT2AKCNA5 | |
| SCHEMBL4590774 | 0.81 | HRH3 (0.45) | HRH3 | |
| SCHEMBL4590536 | 0.81 | FGFR1 (0.46) | AVPR1BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107322-A1 | INDOLE, BENZIMIDAZOLE OR BENZOTRIAZOLE DERIVATIVES INCLUDING A PIPERIDINE OR PIPERAZINE CORE AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |