Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1302344 | 0.71 | — | — | |
| SCHEMBL19181987 | 0.71 | ALDH1A1 (0.36) | ALDH1A1MAPK1TLR7 | |
| SCHEMBL19475484 | 0.69 | ALDH1A1 (0.37) | ALDH1A1MAPK1TLR7 | |
| SCHEMBL1301971 | 0.68 | TLR7 (0.45) | TLR7 | |
| SCHEMBL21369215 | 0.65 | AGTR1 (0.42) | ALDH1A1TLR7 | |
| SCHEMBL2043569 | 0.63 | MAPK1 (0.38) | ALDH1A1MAPK1 | |
| SCHEMBL1300750 | 0.61 | TLR7 (0.41) | ALDH1A1MAPK1TLR7PPARG | |
| SCHEMBL10176962 | 0.58 | PDE10A (0.34) | ALDH1A1 | |
| SCHEMBL12234026 | 0.56 | ALDH1A1 (0.35) | ALDH1A1MAPK1 | |
| SCHEMBL21089365 | 0.56 | TSHR (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045543-A1 | SUBSTITUTED 4H-IMIDAZO [4, 5, 1-IJ] [1, 6] NAPHTHYRIDINE-9-AMINES AND THEIR PHARMACEUTICAL USE | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2008-04-17 | — | — | WO | disclosed |