Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590678 | 0.89 | HRH3 (0.35) | HRH3HPGDL3MBTL1MEN1KMT2A | |
| SCHEMBL4591346 | 0.83 | HRH3 (0.42) | HRH3MEN1KMT2AKDM4EPOLB | |
| SCHEMBL4590727 | 0.82 | HRH3 (0.42) | HRH3HPGDL3MBTL1MEN1KMT2A | |
| SCHEMBL4590031 | 0.80 | HRH3 (0.43) | HRH3MEN1KMT2A | |
| SCHEMBL4590572 | 0.78 | HRH3 (0.44) | HRH3HPGDL3MBTL1MEN1KMT2A | |
| SCHEMBL4590540 | 0.77 | FGFR1 (0.44) | HRH3HPGDMAOBMEN1KMT2A | |
| SCHEMBL4590837 | 0.76 | HRH3 (0.45) | HRH3MEN1KMT2A | |
| SCHEMBL4590551 | 0.76 | HRH3 (0.45) | HRH3MEN1KMT2A | |
| SCHEMBL4590722 | 0.75 | MEN1 (0.44) | HRH3SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL4590774 | 0.75 | HRH3 (0.45) | HRH3SLC6A4FGFR1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107322-A1 | INDOLE, BENZIMIDAZOLE OR BENZOTRIAZOLE DERIVATIVES INCLUDING A PIPERIDINE OR PIPERAZINE CORE AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |