Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.60 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018113 | 0.89 | KCNA5 (0.56) | CTSSCTSKKCNA5KDM4AKMT2A | |
| SCHEMBL30159605 | 0.89 | KCNA5 (0.56) | CTSSCTSKKCNA5KDM4AKMT2A | |
| SCHEMBL18198091 | 0.87 | RIPK1 (0.50) | RIPK1CTSSCTSKKCNA5KMT2A | |
| SCHEMBL12680205 | 0.87 | RPS6KA1 (0.49) | RIPK1CTSSCTSKKCNA5KDM4A | |
| SCHEMBL19950485 | 0.85 | RIPK1 (0.45) | RIPK1CTSSCTSKKCNA5KDM4A | |
| SCHEMBL6232571 | 0.85 | RIPK1 (0.50) | RIPK1CTSSCTSKHTTHPGD | |
| SCHEMBL20256942 | 0.84 | KCNA5 (0.44) | RIPK1CTSSCTSKKCNA5KDM4A | |
| SCHEMBL30968603 | 0.84 | CTSS (0.57) | RIPK1CTSSCTSKKCNA5KMT2A | |
| SCHEMBL30968604 | 0.84 | CTSS (0.57) | RIPK1CTSSCTSKKCNA5KMT2A | |
| SCHEMBL29253672 | 0.84 | CTSS (0.57) | RIPK1CTSSCTSKKCNA5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111566106-B | Compounds as CDK inhibitors | 卡里克治疗有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-111566106-A | 4- [ [ (7-aminopyrazolo [1,5-a ] pyrimidin-5-yl) amino ] methyl ] piperidin-3-ol compounds as CDK inhibitors | 卡里克治疗有限公司 | 2020-08-21 | — | — | CN | disclosed |
| CN-104812746-B | Bruton's tyrosine kinase inhibitors | 弗·哈夫曼-拉罗切有限公司 | 2017-03-08 | — | — | CN | disclosed |
| WO-2008063888-A2 | COMPOUNDS MODULATING C-FMS AND/OR C-KIT ACTIVITY AND USES THEREFOR | PLEXXIKON, INC. (US) | 2008-05-29 | — | — | WO | disclosed |
| US-20070197522-A1 | Dpp-iv inhibitors | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2007-08-23 | — | — | US | disclosed |
| CN-1980892-A | Dpp-IV inhibitors | SANTHERA PHARMACEUTICALS CH (CH) | 2007-06-13 | — | — | CN | disclosed |
| EP-1593671-A1 | DPP-IV inhibitors | Graffinity Pharmaceuticals AG (DE) | 2005-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197522-A1 | Dpp-iv inhibitors | DPP7, DPP4, DPP3 | RIPK1 2671/4885CTSS 261/4885CTSK 185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.