Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19848194 | 0.85 | NPC1 (0.60) | L3MBTL1HPGDPOLBKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL26907985 | 0.84 | FGFR1 (0.57) | L3MBTL1NR1I2KDM4ENPC1TSHR | |
| Hydrochloric Acid SCHEMBL29769980 | 0.84 | FGFR1 (0.57) | L3MBTL1NR1I2KDM4ENPC1TSHR | |
| SCHEMBL19848195 | 0.84 | ALDH1A1 (0.45) | L3MBTL1KDM4ENPC1TSHRNPSR1 | |
| SCHEMBL29069569 | 0.82 | NPC1 (0.43) | L3MBTL1POLBKDM4ENPC1TSHR | |
| Hydrochloric Acid SCHEMBL26907885 | 0.80 | KDM4E (0.42) | L3MBTL1POLBKDM4ENPC1TSHR | |
| Hydrochloric Acid SCHEMBL29770007 | 0.80 | KDM4E (0.42) | L3MBTL1POLBKDM4ENPC1TSHR | |
| Hydrochloric Acid SCHEMBL27115889 | 0.80 | KDM4E (0.42) | L3MBTL1POLBKDM4ENPC1TSHR | |
| Hydrochloric Acid SCHEMBL29769999 | 0.79 | RAB9A (0.39) | L3MBTL1HPGDPOLBKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL26907919 | 0.79 | RAB9A (0.39) | L3MBTL1HPGDPOLBKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107322-A1 | INDOLE, BENZIMIDAZOLE OR BENZOTRIAZOLE DERIVATIVES INCLUDING A PIPERIDINE OR PIPERAZINE CORE AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |