SCHEMBL4590736

SCHEMBL4590736

C=CC(=O)NCC(=O)N(C)c1ccc(Cl)c(COc2cccc3ccc(C)nc23)c1Cl

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8361694 0.92 BDKRB2 (0.79) BDKRB2
SCHEMBL7743013 0.91 BDKRB2 (0.77) BDKRB2
SCHEMBL7748356 0.89 BDKRB2 (0.87) BDKRB2
SCHEMBL7748355 0.89 BDKRB2 (0.87) BDKRB2
SCHEMBL7742398 0.89 BDKRB2 (0.75) BDKRB2
Hydrochloric Acid SCHEMBL7748184 0.88 BDKRB2 (0.75) BDKRB2
SCHEMBL7747321 0.88 BDKRB2 (1.00) BDKRB2
SCHEMBL7747323 0.88 BDKRB2 (1.00) BDKRB2
SCHEMBL7749804 0.88 BDKRB2 (0.87) BDKRB2
SCHEMBL7749801 0.88 BDKRB2 (0.87) BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1881842-A1 USE OF INHIBITORS OF THE RENIN-ANGIOTENSIN SYSTEM FOR THE TREATMENT OF LUNG INJURIES IMBA-Institut für Molekulare Biotechnologie GmbH (AT) 2008-01-30 EP claimed
WO-2006122819-A1 USE OF INHIBITORS OF THE RENIN-ANGIOTENSIN SYSTEM FOR THE TREATMENT OF LUNG INJURIES IMBA-INSTITUT FÜR MOLEKULARE BIOTECHNOLOGIE GMBH (AT) 2006-11-23 WO claimed