Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 20/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749804 | 1.00 | BDKRB2 (0.87) | BDKRB2 | |
| Fr-173657 SCHEMBL29473494 | 0.93 | BDKRB2 (1.00) | BDKRB2 | |
| Fr-173657 SCHEMBL3718364 | 0.93 | BDKRB2 (1.00) | BDKRB2 | |
| Fr-173657 SCHEMBL1559539 | 0.93 | BDKRB2 (1.00) | BDKRB2 | |
| Fr-173657 SCHEMBL7246230 | 0.93 | BDKRB2 (0.99) | BDKRB2 | |
| Fr-173657 SCHEMBL7246238 | 0.93 | BDKRB2 (0.99) | BDKRB2 | |
| SCHEMBL7748006 | 0.92 | BDKRB2 (0.87) | BDKRB2 | |
| SCHEMBL7748002 | 0.92 | BDKRB2 (0.87) | BDKRB2 | |
| SCHEMBL7748356 | 0.92 | BDKRB2 (0.87) | BDKRB2 | |
| SCHEMBL7748355 | 0.92 | BDKRB2 (0.87) | BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0622361-B1 | Heterocyclic compounds as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6169095-B1 | FOR PREVENTION AND/OR TREATMENT OF BRADYKININ OR ITS ANALOGUES MEDIATED DISEASES IN THE EYE, SUCH AS ALLERGY, INFLAMMATION AND PAIN OF THE EYE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-01-02 | — | — | US | disclosed |
| US-5563162-A | CAN BE ADMINISTERD FOR THE TREATMENT OF ALLERGY, INFLAMMATION, AUTOIMMUNE DISEASES, SHOCK OR PAIN IN ANIMALS AND HUMANS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-08 | — | — | US | disclosed |
| EP-0622361-A1 | Heterocyclic compounds as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-02 | — | — | EP | disclosed |