Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | NNMT | P40261 | 4/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29225190 | 0.80 | KMT2A (0.45) | KMT2AMEN1KIF11NNMTSIRT6 | |
| SCHEMBL24786404 | 0.80 | LMNA (0.50) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL185620 | 0.80 | LMNA (0.35) | KMT2AMEN1MAPTALOX15ALDH1A1 | |
| SCHEMBL28940910 | 0.79 | ALDH1A1 (0.52) | KMT2AMEN1KIF11SIRT6SMN1; SMN2 | |
| SCHEMBL15881098 | 0.79 | KMT2A (0.41) | KMT2AMEN1KIF11NNMTSIRT6 | |
| SCHEMBL28998209 | 0.78 | MEN1 (0.43) | KMT2AMEN1KIF11NNMTSMN1; SMN2 | |
| SCHEMBL28724684 | 0.78 | MEN1 (0.43) | KMT2AMEN1KIF11NNMTSIRT6 | |
| SCHEMBL28816899 | 0.78 | KMT2A (0.43) | KMT2AMEN1KIF11NNMTSIRT6 | |
| SCHEMBL9413732 | 0.78 | KMT2A (0.55) | KMT2AMEN1KIF11MAPT | |
| SCHEMBL28882879 | 0.78 | MEN1 (0.39) | KMT2AMEN1KIF11NNMTSIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689664-B | Tricyclic heteroaryl substituted quinoline and azaquinoline compounds as PAR4 inhibitors | 百时美施贵宝公司 | 2022-04-15 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-115279765-A | 1H-pyrazolo [4,3-d ] pyrimidine compounds as Toll-like receptor 7 (TLR 7) agonists | 百时美施贵宝公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115210236-A | 1H-pyrazolo [4,3-d ] pyrimidine compounds as Toll-like receptor 7 (TLR 7) agonists | 百时美施贵宝公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-115210235-A | 1H-pyrazolo [4,3-d ] pyrimidine compounds as Toll-like receptor 7 (TLR 7) agonists | 百时美施贵宝公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-115151546-A | C3-substituted 1H-pyrazolo [4,3-d ] pyrimidine compounds as Toll-like receptor 7 (TLR 7) agonists | 百时美施贵宝公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-115151547-A | 1H-pyrazolo [4,3-d ] pyrimidine compounds as Toll-like receptor 7 (TLR 7) agonists | 百时美施贵宝公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-115151548-A | 1H-pyrazolo [4,3-d ] pyrimidine compounds as Toll-like receptor 7 (TLR 7) agonists | 百时美施贵宝公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-109689664-B | Tricyclic heteroaryl substituted quinoline and azaquinoline compounds as PAR4 inhibitors | 百时美施贵宝公司 | 2022-04-15 | — | — | CN | disclosed |
| WO-2012010578-A1 | SUBSTITUTED METHYL-PYRIMIDIN-5-YL CARBAMATES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-26 | — | — | WO | disclosed |