Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459077 | 1.00 | MEN1 (0.44) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL9125780 | 0.82 | MEN1 (0.44) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL9772165 | 0.79 | ALOX15 (0.40) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL9772166 | 0.79 | ALOX15 (0.40) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL5149959 | 0.79 | — | — | |
| SCHEMBL1248639 | 0.78 | SLC6A5 (0.54) | MEN1CYP1A2KMT2AEPHX2SLC6A5 | |
| SCHEMBL10824725 | 0.78 | SLC6A5 (0.54) | MEN1CYP1A2KMT2AEPHX2SLC6A5 | |
| SCHEMBL10007258 | 0.78 | SLC6A5 (0.54) | MEN1CYP1A2KMT2AEPHX2SLC6A5 | |
| SCHEMBL10007259 | 0.78 | SLC6A5 (0.54) | MEN1CYP1A2KMT2AEPHX2SLC6A5 | |
| SCHEMBL23543287 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010641-A2 | PHARMACEUTICAL COMPOSITION FOR INCREASING CELLULAR HYPOXIC TOLERANCE | UNIVERSITE DE NICE SOPHIA ANTIPOLIS (FR) | 2012-01-26 | — | — | WO | disclosed |