Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | SORD | Q00796 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590830 | 0.80 | BCHE (0.45) | PDE10ATRPC3BCHEACHEHTR3A | |
| SCHEMBL4510882 | 0.77 | PDE10A (0.44) | PDE10ATRPC3BCHEACHEHTR3A | |
| SCHEMBL4502697 | 0.64 | AURKA (0.41) | PDE10A | |
| SCHEMBL2593940 | 0.63 | PDE10A (1.00) | PDE10A | |
| Hydrochloric Acid SCHEMBL7670024 | 0.63 | HTR3A (0.59) | PDE10ATRPC3BCHEACHEHTR3A | |
| SCHEMBL14587776 | 0.62 | TRPC3 (0.68) | TRPC3BCHEACHEHTR3ATP53 | |
| SCHEMBL4512357 | 0.61 | KMT2A (0.53) | PDE10ATP53RAB9AMAPTKDM4E | |
| SCHEMBL13450331 | 0.61 | TRPC3 (1.00) | TRPC3BCHEACHEHTR3ATP53 | |
| SCHEMBL2676103 | 0.61 | BCHE (0.96) | TRPC3BCHEACHEHTR3ATP53 | |
| SCHEMBL2674037 | 0.61 | BCHE (0.90) | TRPC3BCHEACHEHTR3ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008055959-A1 | NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE & INFLAMMATORY DISEASES | GALAPAGOS N.V. (BE) | 2008-05-15 | — | — | WO | claimed |