SCHEMBL4591044

SCHEMBL4591044

C=CCC1=C(O)C(=O)NC1=O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.31
SRD5A1 P18405 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL460153 0.84 ALDH1A1 (0.33)
SCHEMBL4384017 0.74 NPSR1 (0.33)
SCHEMBL8989653 0.74
SCHEMBL15923992 0.74 NPSR1 (0.33)
SCHEMBL670227 0.74
SCHEMBL890999 0.70 XIAP (0.39)
SCHEMBL30791002 0.67 GSK3B (0.43)
SCHEMBL2019993 0.66
SCHEMBL3805627 0.66 GSK3B (0.45)
SCHEMBL3186176 0.65 CYP3A4 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107735422-A Polyurethane aqueous dispersion through peptide functionalization 汉高股份有限及两合公司 2018-02-23 CN claimed
US-7399816-B2 Maleimidyl-containing material and production method thereof FUJI XEROX CO., LTD. (JP) 2008-07-15 US claimed
WO-2007044169-A1 PROCESSES FOR THE PRODUCTION OF HYDROXYALKYLMALEIMIDES ALBEMARLE CORPORATION (US) 2007-04-19 WO claimed
US-20060128943-A1 Maleimidyl-containing material and production method thereof FUJI XEROX CO., LTD. 2006-06-15 US claimed
JP-3012414-A None JP disclosed
US-11878067-B2 Gel compositions containing copolymer of vinylpyrrolidone and acrylic acid L'OREAL (FR) 2024-01-23 US disclosed
WO-2023117986-A1 ENVIRONMENTAL ATTRIBUTES FOR A CURABLE COMPOSITION BASF SE (DE) 2023-06-29 WO disclosed
WO-2021021978-A1 COMPOSITIONS CONTAINING COPOLYMER OF VINYLPYRROLIDONE AND ACRYLIC ACID AND FILM FORMING AGENT L'OREAL (FR) 2021-02-04 WO disclosed
US-20210030635-A1 GEL COMPOSITIONS CONTAINING COPOLYMER OF VINYLPYRROLIDONE AND ACRYLIC ACID L'ORÉAL (FR) 2021-02-04 US disclosed
US-20210030636-A1 EMULSION COMPOSITIONS CONTAINING POLYMER INCLUDING IMIDE GROUP(S), HUMECTANT, AND COPOLYMER OF VINYLPYRROLIDONE AND ACRYLIC ACID L'OREAL (FR) 2021-02-04 US disclosed
CN-111225971-A Improvements in and relating to refreshing of laundry 荷兰联合利华有限公司 2020-06-02 CN disclosed
CN-111212897-A Improvements in and relating to refreshing of laundry 荷兰联合利华有限公司 2020-05-29 CN disclosed
WO-2007044169-A1 PROCESSES FOR THE PRODUCTION OF HYDROXYALKYLMALEIMIDES ALBEMARLE CORPORATION (US) 2007-04-19 WO disclosed
WO-2007044169-A1 PROCESSES FOR THE PRODUCTION OF HYDROXYALKYLMALEIMIDES ALBEMARLE CORPORATION (US) 2007-04-19 WO disclosed
US-7169829-B2 Maleimido-bearing compounds resin composition containing the same and cured articles thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2007-01-30 US disclosed
US-20060128943-A1 Maleimidyl-containing material and production method thereof FUJI XEROX CO., LTD. 2006-06-15 US disclosed
US-20060069213-A1 Ligand immobilization support FUJI XEROX CO., LTD. 2006-03-30 US disclosed
US-20050009947-A1 Maleimido-bearing compounds resin composition containing the same and cured articles thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2005-01-13 US disclosed
EP-1460092-A1 MALEIMIDO-BEARING COMPOUNDS, RESIN COMPOSITIONS CONTAINING THE SAME AND CURED ARTICLES THEREOF Nippon Kayaku Kabushiki Kaisha (JP) 2004-09-22 EP disclosed
JP-H0312414-A CURABLE UNSATURATED IMIDE URETHANE COMPOSITION, ITS PRODUCTION AND CURED MOLDED ARTICLE TEIJIN LTD 1991-01-21 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060128943-A1 Maleimidyl-containing material and production method thereof MEN1, VIP, PTMS PTPN1 3264/4885SRD5A1 1918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.