SCHEMBL460153

SCHEMBL460153

C=CCC1=C(CC=C)C(=O)NC1=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8989653 0.84
SCHEMBL4591044 0.84 PTPN1 (0.31)
SCHEMBL15923992 0.84 NPSR1 (0.33) ALDH1A1NPSR1
SCHEMBL4384017 0.84 NPSR1 (0.33) NPSR1
SCHEMBL670227 0.79
SCHEMBL30791002 0.76 GSK3B (0.43) ALDH1A1NPSR1
SCHEMBL3805627 0.74 GSK3B (0.45)
SCHEMBL3186176 0.73 CYP3A4 (0.35) CYP3A4
SCHEMBL28415709 0.72 NPSR1 (0.35) ALDH1A1NPSR1
SCHEMBL6556277 0.69 ALDH1A1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210336268-A1 METHOD AND SYSTEM FOR FUNCTIONAL CONDUCTIVE POLYMER INITIATED CATHODE ELECTROLYTE INTERFACE FOR SILICON ANODE-BASED LITHIUM ION BATTERIES ENEVATE CORPORATION 2021-10-28 US claimed
US-8609745-B2 Production of ophthalmic devices based on photo-induced step growth polymerization NOVARTIS AG (CH) 2013-12-17 US claimed
EP-2379628-B1 STABILIZERS FOR FLAME RETARDANT POLYMERS CONTAINING ALIPHATICALLY-BOUND BROMINE DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-21 EP claimed
US-20130106007-A1 PRODUCTION OF OPHTHALMIC DEVICES BASED ON PHOTO-INDUCED STEP GROWTH POLYMERIZATION NOVARTIS AG (CH) 2013-05-02 US claimed
US-20110269869-A1 PRODUCTION OF OPHTHALMIC DEVICES BASED ON PHOTO-INDUCED STEP GROWTH POLYMERIZATION ALCON INC. (CH) 2011-11-03 US claimed
EP-2092376-A1 PRODUCTION OF OPHTHALMIC DEVICES BASED ON PHOTO-INDUCED STEP GROWTH POLYMERIZATION Novartis Ag (CH) 2009-08-26 EP claimed
WO-2008076729-A1 PRODUCTION OF OPHTHALMIC DEVICES BASED ON PHOTO-INDUCED STEP GROWTH POLYMERIZATION NOVARTIS AG (CH) 2008-06-26 WO claimed
US-20080143958-A1 Production of ophthalmic devices based on photo-induced step growth polymerization ALCON INC. (CH) 2008-06-19 US claimed
US-20050277061-A1 Polymeric material for laser processing and a laminated body for laser processing thereof, flexographic printing plate and the method of producing the same, and a seal material JSR CORPORATION (JP) 2005-12-15 US claimed
EP-1101608-B1 Articles having imageable coatings KODAK POLYCHROME GRAPHICS CO (US) 2005-01-19 EP claimed
EP-0255601-B1 DIALKYLNALEINIMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDE NIHON BAYER AGROCHEM K.K. (JP) 1991-09-11 EP claimed
US-4729784-A 1-(1,4-benzoxazin-3-on-6-yl)-dialkylmaleimides and use as herbicides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1988-03-08 US claimed
EP-0255601-A2 Dialkylnaleinimides, process for their preparation and their use as herbicide NIHON BAYER AGROCHEM K.K. (JP) 1988-02-10 EP claimed
US-4585848-A HIGH STRENGTH, SOLVENT RESISTANCE EVANS EDWIN R (US) 1986-04-29 US claimed
US-4459305-A INSECTICIDE, MITICIDE DAINIPPON SOCHUGIKU KABUSHIKI KAISHA (JP) 1984-07-10 US claimed
US-4031235-A Insecticidal substituted acetate compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-06-21 US claimed
JP-54067030-A None JP disclosed
JP-52127996-A None JP disclosed
US-4031235-A Insecticidal substituted acetate compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-06-21 US disclosed
US-3996244-A Insecticidal esters of substituted furan methanol SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269869-A1 PRODUCTION OF OPHTHALMIC DEVICES BASED ON PHOTO-INDUCED STEP GROWTH POLYMERIZATION CRYAA, CRYZ, CRYAB ALDH1A1 2409/4885CYP3A4 3526/4885NPSR1 3359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.