Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 2/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | FLT1 | P17948 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | ABL2 | P42684 | 2/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 4/20 | 0.33 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3564653 | 0.90 | ADH1A (0.49) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL4590751 | 0.82 | ADH1A (0.36) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL3565156 | 0.77 | ADH1A (0.36) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL3566213 | 0.77 | ADH1A (0.38) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL3885928 | 0.77 | ADH1A (0.38) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL3555079 | 0.76 | CA2 (0.42) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL3562214 | 0.76 | CA2 (0.42) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL3846849 | 0.76 | ADH1A (0.39) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL3555601 | 0.76 | ADH1A (0.39) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL3566195 | 0.76 | ADH1A (0.39) | ADH1AKITFLT1KDRABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008039087-A2 | INDOLINE DERIVATIVES AND USES THEREOF | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-04-03 | — | — | WO | disclosed |