Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 8/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821924 | 1.00 | BCHE (0.56) | BCHEMAOBNPC1RAB9AATM | |
| SCHEMBL4680830 | 0.94 | PTPN1 (0.51) | BCHEMAOBNPC1RAB9AATM | |
| SCHEMBL2825700 | 0.93 | NPC1 (0.56) | BCHEMAOBNPC1RAB9AATM | |
| SCHEMBL8259525 | 0.90 | SMN1; SMN2 (0.51) | BCHEMAOBFAAHMGLLCYP1A2 | |
| SCHEMBL4589756 | 0.89 | KDM4E (0.49) | BCHEMAOBNPC1RAB9AATM | |
| SCHEMBL2824404 | 0.89 | KDM4E (0.49) | BCHEMAOBNPC1RAB9AATM | |
| SCHEMBL13910106 | 0.89 | ALDH1A1 (0.54) | BCHEMAOBNPC1RAB9AMGLL | |
| SCHEMBL8249953 | 0.87 | GFER (0.56) | RAB9ACYP1A2CYP2C9CYP2C19HSD11B1 | |
| SCHEMBL8259627 | 0.87 | RAB9A (0.49) | BCHEMAOBNPC1RAB9AATM | |
| SCHEMBL936129 | 0.85 | BCHE (0.53) | BCHEMAOBRAB9ACCR3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893200-A2 | CARBAMATE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX Pharma S.A. (CH) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006123244-A2 | CARBAMATE DERIVATIVES AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMA SA (CH) | 2006-11-23 | — | — | WO | disclosed |